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    Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [ Mus musculus (house mouse) ]

    Gene ID: 101502, updated on 25-May-2017
    Official Symbol
    Hsd3b7provided by MGI
    Official Full Name
    hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7provided by MGI
    Primary source
    MGI:MGI:2141879
    See related
    Ensembl:ENSMUSG00000042289 Vega:OTTMUSG00000058631
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI195443; BB098564
    Orthologs
    Location:
    7; 7 F3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (127800601..127803803)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134944123..134947316)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene ORAI calcium release-activated calcium modulator 3 Neighboring gene SET domain containing 1A Neighboring gene syntaxin 1B Neighboring gene syntaxin 4A (placental)

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    B cell chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cholesterol catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    3 beta-hydroxysteroid dehydrogenase type 7
    Names
    3 beta-hydroxysteroid dehydrogenase type VII
    3-beta-HSD VII
    3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase
    c(27) 3-beta-HSD
    cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase
    NP_001035774.1
    NP_598704.2
    XP_017177394.1
    XP_017177395.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040684.1NP_001035774.1  3 beta-hydroxysteroid dehydrogenase type 7 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC149222, BB854484, BY133253, CB951288
      Conserved Domains (2) summary
      pfam01073
      Location:2256
      3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family
      cl21454
      Location:1334
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. NM_133943.2NP_598704.2  3 beta-hydroxysteroid dehydrogenase type 7 isoform a

      See identical proteins and their annotated locations for NP_598704.2

      Status: VALIDATED

      Source sequence(s)
      AC149222, BB854484, CB951288
      Consensus CDS
      CCDS40145.1
      UniProtKB/Swiss-Prot
      Q9EQC1
      Related
      ENSMUSP00000036245.5, OTTMUSP00000018894, ENSMUST00000046863.11, OTTMUST00000042018
      Conserved Domains (2) summary
      cd09811
      Location:11361
      3b-HSD_HSDB1_like_SDR_e; human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs
      pfam01073
      Location:13283
      3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      127800601..127803803
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321905.1XP_017177394.1  3 beta-hydroxysteroid dehydrogenase type 7 isoform X1

    2. XM_017321906.1XP_017177395.1  3 beta-hydroxysteroid dehydrogenase type 7 isoform X1

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