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    flavivirus polyprotein gene flavivirus polyprotein [ West Nile virus ]

    Gene ID: 5714902, updated on 22-Oct-2016
    Gene symbol
    flavivirus polyprotein gene
    Gene description
    flavivirus polyprotein
    Locus tag
    WNVNY99_gp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    West Nile virus (strain: NY99, isolate: 385-99, gb-acronym: WNV)
    Lineage
    Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Japanese encephalitis virus group
    Sequence:
    NC_009942.1 (97..10398)

    NC_009942.1Genomic Context describing neighboring genes

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Names
    flavivirus polyprotein
    truncated flavivirus polyprotein WARF4
    truncated flavivirus polyprotein NS1 prime
    capsid protein C
    anchored capsid protein C
    membrane glycoprotein precursor M
    envelope protein E
    nonstructural protein NS1
    nonstructural protein NS2A
    nonstructural protein NS2B
    nonstructural protein NS3
    nonstructural protein NS4A
    nonstructural protein NS4B
    RNA-dependent RNA polymerase NS5
    membrane glycoprotein M
    protein 2K
    protein pr
    N-NS4B/WARF4
    nonstructural protein NS1 prime
    YP_006485883.2
    • NS1'; Truncated version of polyprotein that will be produced when programmed ribosomal frameshifting occurs at nt 3552; Truncated version of polyprotein and NS1' protein have been added and annotated with the kind help of Dr. David Karlin (Department of Zoology, University of Oxford, UK) and Dr. Andrew Firth (Department of Pathology, University of Cambridge, UK)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009942.1 Reference assembly

      Range
      97..10398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_001527877.1 flavivirus polyprotein [West Nile virus]

      See identical proteins and their annotated locations for YP_001527877.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q3HM13
      Conserved Domains (28) summary
      pfam01003
      Location:6105
      Flavi_capsid; Flavivirus capsid protein C
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
      pfam01004
      Location:98167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:781
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:98167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:781
      Flavi_propep; Flavivirus polyprotein propeptide
      cd12149
      Location:308400
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:405501
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      pfam00869
      Location:3299
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
      pfam00948
      Location:2352
      Flavi_NS1; Flavivirus non-structural Protein NS1
      pfam01005
      Location:12164
      Flavi_NS2A; Flavivirus non-structural protein NS2A
      pfam01002
      Location:6131
      Flavi_NS2B; Flavivirus non-structural protein NS2B
      smart00487
      Location:181352
      DEXDc; DEAD-like helicases superfamily
      pfam00949
      Location:19167
      Peptidase_S7; Peptidase S7, Flavivirus NS3 serine protease
      pfam07652
      Location:186331
      Flavi_DEAD; Flavivirus DEAD domain
      cl21455
      Location:357465
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
      pfam01350
      Location:5147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01350
      Location:5147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01349
      Location:1246
      Flavi_NS4B; Flavivirus non-structural protein NS4B
      pfam00972
      Location:255894
      Flavi_NS5; Flavivirus RNA-directed RNA polymerase
      pfam01728
      Location:55224
      FtsJ; FtsJ-like methyltransferase
      pfam01004
      Location:98167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:781
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:98167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:781
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01350
      Location:5147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01350
      Location:5147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01570
      Location:791
      Flavi_propep; Flavivirus polyprotein propeptide
    2. YP_009246337.1 truncated flavivirus polyprotein WARF4 [West Nile virus]

      Status: PROVISIONAL

    3. YP_009246339.1 N-NS4B/WARF4

    4. YP_006485883.2 truncated flavivirus polyprotein NS1 prime [West Nile virus]

      Status: PROVISIONAL

      Conserved Domains (7) summary
      cd12149
      Location:598690
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:695791
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
      pfam00869
      Location:293589
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
      pfam00948
      Location:7931143
      Flavi_NS1; Flavivirus non-structural Protein NS1
      pfam01004
      Location:221290
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:130204
      Flavi_propep; Flavivirus polyprotein propeptide
    5. YP_009246338.1 nonstructural protein NS1 prime

      Conserved Domains (1) summary
      pfam00948
      Location:2352
      Flavi_NS1; Flavivirus non-structural Protein NS1
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