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    Glra3 glycine receptor, alpha 3 subunit [ Mus musculus (house mouse) ]

    Gene ID: 110304, updated on 22-Apr-2017
    Official Symbol
    Glra3provided by MGI
    Official Full Name
    glycine receptor, alpha 3 subunitprovided by MGI
    Primary source
    MGI:MGI:95749
    See related
    Ensembl:ENSMUSG00000038257 Vega:OTTMUSG00000036483
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Orthologs
    Location:
    8 B2; 8 29.69 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (55940411..56125352)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (58419622..58604149)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene methyltransferase like 13 pseudogene Neighboring gene a disintegrin and metallopeptidase domain 29 Neighboring gene ribosomal protein S7 pseudogene Neighboring gene hydroxyprostaglandin dehydrogenase 15 (NAD) Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular ligand-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to extracellular-glycine-gated chloride channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    extracellular-glycine-gated chloride channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to glycine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    glycine-gated chloride ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    transmitter-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular response to amino acid stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to ethanol ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to zinc ion ISO
    Inferred from Sequence Orthology
    more info
     
    chloride transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    chloride transport IEA
    Inferred from Electronic Annotation
    more info
     
    glutamate receptor clustering IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    response to amino acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    synaptic transmission, glycinergic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    GABA-ergic synapse IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    chloride channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycine-gated chloride channel complex ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    glycine receptor subunit alpha-3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080438.2NP_536686.2  glycine receptor subunit alpha-3

      See identical proteins and their annotated locations for NP_536686.2

      Status: VALIDATED

      Source sequence(s)
      AK038618, AY230204
      Consensus CDS
      CCDS40340.1
      UniProtKB/Swiss-Prot
      Q91XP5
      UniProtKB/TrEMBL
      G5E811
      Related
      ENSMUSP00000000275.7, OTTMUSP00000051884, ENSMUST00000000275.8, OTTMUST00000093512
      Conserved Domains (3) summary
      TIGR00860
      Location:28467
      LIC; Cation transporter family protein
      pfam02931
      Location:63269
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:276464
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      55940411..56125352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509247.2XP_006509310.1  glycine receptor subunit alpha-3 isoform X1

      Conserved Domains (3) summary
      TIGR00860
      Location:28452
      LIC; Cation transporter family protein
      pfam02931
      Location:63269
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:276449
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
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