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    Olig2 oligodendrocyte transcription factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304103, updated on 26-Sep-2017
    Official Symbol
    Olig2provided by RGD
    Official Full Name
    oligodendrocyte transcription factor 2provided by RGD
    Primary source
    RGD:1307098
    See related
    Ensembl:ENSRNOG00000028658
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    Location:
    11q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31389514..31392890)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (34998542..35001918)

    Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554018 Neighboring gene uncharacterized LOC108352305 Neighboring gene oligodendrocyte transcription factor 1 Neighboring gene interferon alpha and beta receptor subunit 2

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    HMG box domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    HMG box domain binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transcription factor activity, sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    myelination IEA
    Inferred from Electronic Annotation
    more info
     
    myelination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nervous system development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuron fate commitment IEA
    Inferred from Electronic Annotation
    more info
     
    neuron fate commitment ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    oligodendrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of oligodendrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spinal cord motor neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    spinal cord motor neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spinal cord oligodendrocyte cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spinal cord oligodendrocyte cell fate specification IEA
    Inferred from Electronic Annotation
    more info
     
    spinal cord oligodendrocyte cell fate specification ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    thalamus development IEA
    Inferred from Electronic Annotation
    more info
     
    thalamus development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    oligodendrocyte transcription factor 2
    Names
    oligodendrocyte lineage transcription factor 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100557.1NP_001094027.1  oligodendrocyte transcription factor 2

      See identical proteins and their annotated locations for NP_001094027.1

      Status: VALIDATED

      Source sequence(s)
      AC112633
      UniProtKB/TrEMBL
      G3V612
      Related
      ENSRNOP00000000325.4, ENSRNOT00000000325.6
      Conserved Domains (1) summary
      smart00353
      Location:114168
      HLH; helix loop helix domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

      Range
      31389514..31392890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000079.1 Alternate Rn_Celera

      Range
      30143763..30147131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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