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    Trim24 tripartite motif-containing 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500084, updated on 4-Feb-2018
    Symbol
    Trim24provided by RGD
    Full Name
    tripartite motif-containing 24provided by RGD
    Primary source
    RGD:1560596
    See related
    Ensembl:ENSRNOG00000013251
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Liver (RPKM 118.2), Testes (RPKM 75.6) and 9 other tissues See more
    Orthologs
    Location:
    4q22
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (65632278..65684746)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (65451992..65504097)

    Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552017 Neighboring gene aldo-keto reductase family 1, member D1 Neighboring gene SVOP like Neighboring gene ATPase H+ transporting V0 subunit a4 Neighboring gene uncharacterized LOC103692100 Neighboring gene similar to KIAA1549 protein Neighboring gene transmembrane protein 213

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    estrogen response element binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    ligand-dependent nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    lysine-acetylated histone binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    molecular_function ND
    No biological Data available
    more info
     
    p53 binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    calcium ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cellular response to estrogen stimulus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of protein stability ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of vitamin D receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to peptide hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nuclear euchromatin ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT nucleolus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    perichromatin fibrils ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    transcription intermediary factor 1-alpha
    Names
    Ab2-427
    NP_001037731.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044266.1NP_001037731.1  transcription intermediary factor 1-alpha

      See identical proteins and their annotated locations for NP_001037731.1

      Status: PROVISIONAL

      Source sequence(s)
      AY325210
      UniProtKB/TrEMBL
      Q7TP39
      Related
      ENSRNOP00000050587.4, ENSRNOT00000047954.4
      Conserved Domains (1) summary
      cl02556
      Location:389446
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

      Range
      65632278..65684746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000072.1 Alternate Rn_Celera

      Range
      61686473..61738396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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