Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    METTL18 methyltransferase like 18 [ Homo sapiens (human) ]

    Gene ID: 92342, updated on 12-Mar-2017
    Official Symbol
    METTL18provided by HGNC
    Official Full Name
    methyltransferase like 18provided by HGNC
    Primary source
    HGNC:HGNC:28793
    See related
    Ensembl:ENSG00000171806 MIM:615255; Vega:OTTHUMG00000035813
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HPM1; AsTP2; C1orf156
    Orthologs
    Location:
    1q24.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (169792524..169794976, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (169761670..169764088, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene selectin E Neighboring gene uncharacterized LOC101928628 Neighboring gene chromosome 1 open reading frame 112 Neighboring gene RNA, 7SL, cytoplasmic 333, pseudogene Neighboring gene SCY1 like pseudokinase 3 Neighboring gene kinesin associated protein 3 Neighboring gene RNA, 7SL, cytoplasmic 269, pseudogene

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC9084

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    histidine protein methyltransferase 1 homolog
    Names
    arsenic-transactivated protein 2
    methyltransferase-like protein 18

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320199.1NP_001307128.1  histidine protein methyltransferase 1 homolog

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      BC008679, BG614785, HY159746
      Consensus CDS
      CCDS1284.1
      UniProtKB/Swiss-Prot
      O95568
      UniProtKB/TrEMBL
      A0A024R8Y7
      Conserved Domains (1) summary
      cl17173
      Location:165324
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    2. NM_001320201.1NP_001307130.1  histidine protein methyltransferase 1 homolog

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      BC008679
      Consensus CDS
      CCDS1284.1
      UniProtKB/Swiss-Prot
      O95568
      UniProtKB/TrEMBL
      A0A024R8Y7
      Related
      ENSP00000307077, OTTHUMP00000033957, ENST00000303469, OTTHUMT00000087110
      Conserved Domains (1) summary
      cl17173
      Location:165324
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    3. NM_033418.3NP_219486.1  histidine protein methyltransferase 1 homolog

      See identical proteins and their annotated locations for NP_219486.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
      Source sequence(s)
      BC008679, HY159746
      Consensus CDS
      CCDS1284.1
      UniProtKB/Swiss-Prot
      O95568
      UniProtKB/TrEMBL
      A0A024R8Y7
      Related
      ENSP00000307975, OTTHUMP00000033956, ENST00000310392, OTTHUMT00000087109
      Conserved Domains (1) summary
      cl17173
      Location:165324
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

      Range
      169792524..169794976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006711627.3XP_006711690.1  histidine protein methyltransferase 1 homolog isoform X1

      See identical proteins and their annotated locations for XP_006711690.1

      UniProtKB/Swiss-Prot
      O95568
      UniProtKB/TrEMBL
      A0A024R8Y7
      Conserved Domains (1) summary
      cl17173
      Location:165324
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    Alternate CHM1_1.1

    Genomic

    1. NC_018912.2 Alternate CHM1_1.1

      Range
      171183818..171186265 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center