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    CELA1 chymotrypsin like elastase family member 1 [ Sus scrofa (pig) ]

    Gene ID: 396766, updated on 19-May-2018
    Gene symbol
    CELA1
    Gene description
    chymotrypsin like elastase family member 1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Also known as
    ELA1; ELS1; Elastase-1
    Expression
    Biased expression in ovary (RPKM 10.0) and spleen (RPKM 2.4) See more
    Orthologs
    See CELA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018085018.1 (62822..89758)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (17250142..17279128, complement)

    NW_018085018.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 6 Neighboring gene bridging integrator 2 Neighboring gene small cell adhesion glycoprotein Neighboring gene DAZ associated protein 2

    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    chymotrypsin-like elastase family member 1
    Names
    pancreatic elastase I
    NP_998988.1
    XP_005655631.2
    XP_020937363.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213823.1NP_998988.1  chymotrypsin-like elastase family member 1 preproprotein

      See identical proteins and their annotated locations for NP_998988.1

      Status: VALIDATED

      Source sequence(s)
      D00160
      UniProtKB/Swiss-Prot
      P00772
      Conserved Domains (2) summary
      smart00020
      Location:26259
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:27262
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NW_018085018.1 Reference Sscrofa11.1 Primary Assembly

      Range
      62822..89758
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005655574.3XP_005655631.2  chymotrypsin-like elastase family member 1 isoform X1

      Conserved Domains (1) summary
      cd00190
      Location:67302
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    2. XM_021081704.1XP_020937363.1  chymotrypsin-like elastase family member 1 isoform X2

      Conserved Domains (1) summary
      cd00190
      Location:27262
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
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