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    Nasp nuclear autoantigenic sperm protein (histone-binding) [ Mus musculus (house mouse) ]

    Gene ID: 50927, updated on 22-Apr-2017
    Official Symbol
    Naspprovided by MGI
    Official Full Name
    nuclear autoantigenic sperm protein (histone-binding)provided by MGI
    Primary source
    MGI:MGI:1355328
    See related
    Ensembl:ENSMUSG00000028693 Vega:OTTMUSG00000009439
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Epcs32; Nasp-T; AI131596; AI317140; D4Ertd767e; 5033430J04Rik
    Orthologs
    Location:
    4 D1; 4 53.24 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (116601052..116627951, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (116273657..116300556, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene GC-rich promoter binding protein 1-like 1 Neighboring gene RIKEN cDNA C530005A16 gene Neighboring gene coiled-coil domain containing 17 Neighboring gene aldo-keto reductase family 1, member A1 (aldehyde reductase) Neighboring gene expressed sequence AV051173 Neighboring gene peroxiredoxin 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Hsp90 protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA replication IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA replication-dependent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    DNA replication-independent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    blastocyst development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone exchange IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    nuclear autoantigenic sperm protein
    Names
    nasp
    somatic histone binding protein NASP

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081475.1NP_001074944.1  nuclear autoantigenic sperm protein isoform 1

      See identical proteins and their annotated locations for NP_001074944.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and lacks an alternate in-frame exon in the coding region, compared to variant 2. It encodes isoform 1, which is shorter than isoform 2.
      Source sequence(s)
      AK083333, AL669953
      Consensus CDS
      CCDS38852.1
      UniProtKB/Swiss-Prot
      Q99MD9
      UniProtKB/TrEMBL
      B1AU76
      Related
      ENSMUSP00000030457.5, OTTMUSP00000009824, ENSMUST00000030457.11, OTTMUST00000021501
      Conserved Domains (3) summary
      sd00006
      Location:203231
      TPR; TPR repeat [structural motif]
      pfam10516
      Location:203240
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:200277
      TPR_12; Tetratricopeptide repeat
    2. NM_001284229.1NP_001271158.1  nuclear autoantigenic sperm protein isoform 3

      See identical proteins and their annotated locations for NP_001271158.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks two alternate in-frame exons in the coding region, compared to variant 2. It encodes isoform 3, which is shorter than isoform 2.
      Source sequence(s)
      AF095722, AK083333, AL669953
      Consensus CDS
      CCDS71451.1
      UniProtKB/Swiss-Prot
      Q99MD9
      Related
      ENSMUSP00000079946.4, OTTMUSP00000009825, ENSMUST00000081182.4, OTTMUST00000021502
      Conserved Domains (3) summary
      sd00006
      Location:176204
      TPR; TPR repeat [structural motif]
      pfam10516
      Location:176213
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:173250
      TPR_12; Tetratricopeptide repeat
    3. NM_016777.3NP_058057.3  nuclear autoantigenic sperm protein isoform 2

      See identical proteins and their annotated locations for NP_058057.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2).
      Source sequence(s)
      AL669953, BX004835
      Consensus CDS
      CCDS18513.1
      UniProtKB/TrEMBL
      B1AU75
      Related
      ENSMUSP00000030456.7, OTTMUSP00000009823, ENSMUST00000030456.13, OTTMUST00000021500
      Conserved Domains (3) summary
      sd00006
      Location:528556
      TPR; TPR repeat [structural motif]
      pfam10516
      Location:528565
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:525602
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      116601052..116627951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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