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    Fcgr4 Fc receptor, IgG, low affinity IV [ Mus musculus (house mouse) ]

    Gene ID: 246256, updated on 6-Sep-2017
    Official Symbol
    Fcgr4provided by MGI
    Official Full Name
    Fc receptor, IgG, low affinity IVprovided by MGI
    Primary source
    MGI:MGI:2179523
    See related
    Ensembl:ENSMUSG00000059089 Vega:OTTMUSG00000022168
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fcrl3; CD16-2; FcgRIV; Fcgr3a; FcgammaRIV; 4833442P21Rik
    Orthologs
    Location:
    1 H3; 1 78.53 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (171018926..171029761)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (172949057..172959892)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34968 Neighboring gene uncharacterized LOC102638466 Neighboring gene nuclear encoded tRNA asparagine 6 (anticodon GTT) Neighboring gene predicted gene, 35090 Neighboring gene nuclear encoded tRNA aspartic acid 4 (anticodon GTC)

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    IgE binding IEA
    Inferred from Electronic Annotation
    more info
     
    IgE receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    IgG binding IEA
    Inferred from Electronic Annotation
    more info
     
    IgG receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to lipopolysaccharide ISO
    Inferred from Sequence Orthology
    more info
     
    neutrophil activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of bone resorption IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of sensory perception of pain ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    low affinity immunoglobulin gamma Fc region receptor IV
    Names
    Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16)
    Fc gammaRIV
    Fc receptor-like 3
    low affinity immunoglobulin gamma Fc region receptor III-A

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144559.2NP_653142.2  low affinity immunoglobulin gamma Fc region receptor IV precursor

      See identical proteins and their annotated locations for NP_653142.2

      Status: VALIDATED

      Source sequence(s)
      AC115959, AK076532, AK087863
      Consensus CDS
      CCDS15476.1
      UniProtKB/Swiss-Prot
      A0A0B4J1G0
      Related
      ENSMUSP00000077873.4, OTTMUSP00000024985, ENSMUST00000078825.4, OTTMUST00000052638
      Conserved Domains (2) summary
      cd05752
      Location:25103
      Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
      cd05753
      Location:107188
      Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      171018926..171029761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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