Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    ZC3H12D zinc finger CCCH-type containing 12D [ Homo sapiens (human) ]

    Gene ID: 340152, updated on 8-Nov-2017
    Official Symbol
    ZC3H12Dprovided by HGNC
    Official Full Name
    zinc finger CCCH-type containing 12Dprovided by HGNC
    Primary source
    HGNC:HGNC:21175
    See related
    Ensembl:ENSG00000178199 MIM:611106; Vega:OTTHUMG00000015786
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TFL; p34; MCPIP4; C6orf95; dJ281H8.1
    Expression
    Biased expression in lymph node (RPKM 4.6), appendix (RPKM 3.5) and 11 other tissues See more
    Orthologs
    Location:
    6q25.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 6 NC_000006.12 (149447630..149485012, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (149768766..149806148, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 2 Neighboring gene fatty acid binding protein 12 pseudogene 1 Neighboring gene small ubiquitin-like modifier 4 Neighboring gene coiled-coil domain containing 59 pseudogene Neighboring gene peptidylprolyl isomerase like 4 Neighboring gene RNA, U7 small nuclear 3 pseudogene

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • FLJ00361, FLJ46041

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    3'-UTR-mediated mRNA destabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleic acid phosphodiester bond hydrolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic ribonucleoprotein granule IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    Preferred Names
    probable ribonuclease ZC3H12D
    Names
    Zinc finger CCCH domain-containing protein 12D
    transformed follicular lymphoma
    tumor suppressor TFL

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207360.2NP_997243.2  probable ribonuclease ZC3H12D

      See identical proteins and their annotated locations for NP_997243.2

      Status: VALIDATED

      Source sequence(s)
      AL031133
      Consensus CDS
      CCDS47500.2
      UniProtKB/Swiss-Prot
      A2A288
      Related
      ENSP00000386616.3, OTTHUMP00000183473, ENST00000409806.7, OTTHUMT00000286400
      Conserved Domains (2) summary
      PHA03215
      Location:286350
      PHA03215; nuclear protein UL24; Provisional
      pfam11977
      Location:88244
      RNase_Zc3h12a; Zc3h12a-like Ribonuclease NYN domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p7 Primary Assembly

      Range
      149447630..149485012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018917.2 Alternate CHM1_1.1

      Range
      150033515..150070897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center