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    BCL6 B-cell CLL/lymphoma 6 [ Gallus gallus (chicken) ]

    Gene ID: 424912, updated on 12-Mar-2017
    Symbol
    BCL6provided by CGNC
    Full Name
    B-cell CLL/lymphoma 6provided by CGNC
    Primary source
    CGNC:5559
    See related
    Ensembl:ENSGALG00000007357
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    Location:
    chromosome: 9
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Gallus_gallus-5.0 (GCF_000002315.4) 9 NC_006096.4 (14830563..14846808)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 9 NC_006096.3 (14257892..14274167)

    Chromosome 9 - NC_006096.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101751200 Neighboring gene uncharacterized LOC107054097 Neighboring gene uncharacterized LOC107054078 Neighboring gene somatostatin

    • FoxO signaling pathway, organism-specific biosystem (from KEGG)
      FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    B cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Rho protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    actin cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cell morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cellular response to DNA damage stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    erythrocyte development ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    germinal center formation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of Rho protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of cell growth ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of cell-matrix adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of isotype switching to IgE isotypes ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of mast cell cytokine production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    negative regulation of type 2 immune response ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of B cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of cellular component movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein import into nucleus, translocation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of inflammatory response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of inflammatory response ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of memory T cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    type 2 immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    colocalizes_with replication fork ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Preferred Names
    B-cell lymphoma 6 protein homolog
    Names
    B-cell CLL/lymphoma 6 (zinc finger protein 51)
    BCL6

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012930.1NP_001012948.1  B-cell lymphoma 6 protein homolog

      See identical proteins and their annotated locations for NP_001012948.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ719545
      UniProtKB/Swiss-Prot
      Q5ZM39
      Related
      ENSGALP00000011884, ENSGALT00000011898
      Conserved Domains (4) summary
      smart00225
      Location:33129
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:578598
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22126
      BTB; BTB/POZ domain
      pfam13465
      Location:590615
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Gallus_gallus-5.0 Primary Assembly

    Genomic

    1. NC_006096.4 Reference Gallus_gallus-5.0 Primary Assembly

      Range
      14830563..14846808
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015291406.1XP_015146892.1  B-cell lymphoma 6 protein homolog isoform X1

      UniProtKB/TrEMBL
      F1NBN7
      Conserved Domains (4) summary
      smart00225
      Location:33129
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:578598
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22126
      BTB; BTB/POZ domain
      pfam13465
      Location:590615
      zf-H2C2_2; Zinc-finger double domain
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