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    Rab17 RAB17, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 19329, updated on 9-Jul-2017
    Official Symbol
    Rab17provided by MGI
    Official Full Name
    RAB17, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:104640
    See related
    Ensembl:ENSMUSG00000026304 Vega:OTTMUSG00000026752
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW413472
    Orthologs
    Location:
    1 D; 1 45.84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (90958133..90969674, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (92854710..92866197, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene melanophilin Neighboring gene prolactin releasing hormone Neighboring gene leucine rich repeat (in FLII) interacting protein 1 Neighboring gene predicted gene, 35443 Neighboring gene RNA binding motif protein 44

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    endocytic recycling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment of melanosome localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    filopodium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    melanosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of filopodium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    melanosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    recycling endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    recycling endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159725.2NP_001153197.2  ras-related protein Rab-17

      See identical proteins and their annotated locations for NP_001153197.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
      Source sequence(s)
      AK009707, BC051071
      Consensus CDS
      CCDS15156.1
      UniProtKB/Swiss-Prot
      P35292
      UniProtKB/TrEMBL
      Q0PD39
      Related
      ENSMUSP00000122178.1, OTTMUSP00000033110, ENSMUST00000131428.7, OTTMUST00000066164
      Conserved Domains (2) summary
      cd01860
      Location:21181
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
      pfam00071
      Location:21182
      Ras; Ras family
    2. NM_008998.4NP_033024.1  ras-related protein Rab-17

      See identical proteins and their annotated locations for NP_033024.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
      Source sequence(s)
      AK075591, BC051071
      Consensus CDS
      CCDS15156.1
      UniProtKB/Swiss-Prot
      P35292
      UniProtKB/TrEMBL
      Q0PD39
      Related
      ENSMUSP00000027529.5, OTTMUSP00000033109, ENSMUST00000027529.11, OTTMUST00000066163
      Conserved Domains (2) summary
      cd01860
      Location:21181
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
      pfam00071
      Location:21182
      Ras; Ras family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      90958133..90969674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529263.2XP_006529326.1  ras-related protein Rab-17 isoform X1

      See identical proteins and their annotated locations for XP_006529326.1

      UniProtKB/Swiss-Prot
      P35292
      UniProtKB/TrEMBL
      Q0PD39
      Conserved Domains (2) summary
      cd01860
      Location:21181
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
      pfam00071
      Location:21182
      Ras; Ras family
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