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    ALD6 aldehyde dehydrogenase (NADP(+)) ALD6 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856044, updated on 9-Apr-2017
    Gene symbol
    ALD6
    Gene description
    aldehyde dehydrogenase (NADP(+)) ALD6
    Primary source
    SGD:S000005982
    Locus tag
    YPL061W
    Gene type
    protein coding
    RNA name
    aldehyde dehydrogenase (NADP(+)) ALD6
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ALD1
    See ALD6 in Map Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (432588..434090)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene protein translocase subunit TIM50 Neighboring gene hypothetical protein Neighboring gene Mfm1p Neighboring gene tRNA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    aldehyde dehydrogenase (NAD) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    aldehyde dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
     
    aldehyde dehydrogenase [NAD(P)+] activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    aldehyde dehydrogenase [NAD(P)+] activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    NADPH regeneration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acetate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ethanol catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    aldehyde dehydrogenase (NADP(+)) ALD6
    NP_015264.1
    • Cytosolic aldehyde dehydrogenase; activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      432588..434090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183875.1NP_015264.1  TPA: aldehyde dehydrogenase (NADP(+)) ALD6 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_015264.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54115
      Conserved Domains (1) summary
      cd07091
      Location:23498
      ALDH_F1-2_Ald2-like; ALDH subfamily: ALDH families 1and 2, including 10-formyltetrahydrofolate dehydrogenase, NAD+-dependent retinal dehydrogenase 1 and related proteins
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