Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    THI7 thiamine transporter THI7 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850938, updated on 5-Nov-2017
    Gene symbol
    THI7
    Gene description
    thiamine transporter THI7
    Primary source
    SGD:S000004227
    Locus tag
    YLR237W
    Gene type
    protein coding
    RNA name
    thiamine transporter THI7
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    THI10
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (612367..614163)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase 3 Neighboring gene hypothetical protein Neighboring gene Far10p Neighboring gene lipoyl(octanoyl) transferase LIP2

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    nucleobase transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    thiamine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    thiamine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    nucleobase transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    thiamine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    thiamine transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    thiamine transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell periphery IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    thiamine transporter THI7
    NP_013338.1
    • Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      612367..614163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182124.1NP_013338.1  TPA: thiamine transporter THI7 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013338.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05998
      Conserved Domains (1) summary
      cd11482
      Location:27505
      SLC-NCS1sbd_NRT1-like; nucleobase-cation-symport-1 (NCS1) transporter NRT1-like; solute-binding domain
    Support Center