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    ftsY Signal Recognition Particle (SRP) receptor [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947978, updated on 25-May-2017
    Gene symbol
    ftsY
    Gene description
    Signal Recognition Particle (SRP) receptor
    Primary source
    EcoGene:EG10346
    Locus tag
    b3464
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3448; JW3429
    Summary
    FtsY is found as both membrane-associated isoforms and as shorter soluble isoforms which are lacking the N-terminal 14 aa; FtsY is attached to the cytoplasmic membrane by its association with the secYEG translocon and the FtsY N-terminal 14 aa cleavable membrane anchor facilitates this association by first transiently anchoring FtsY to the membrane (Luirink, 1994; Weiche, 2008). [More information is available at EcoGene: EG10346].
    Sequence:
    NC_000913.3 (3602750..3604243, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase, sigma 32 (sigma H) factor Neighboring gene putative ABC transporter permease Neighboring gene cell division ATP-binding protein Neighboring gene 16S rRNA m(2)G966 methyltransferase, SAM-dependent Neighboring gene DUF1145 family protein Neighboring gene DUF2500 family protein

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    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    GTP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    SRP-dependent cotranslational protein targeting to membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intrinsic component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    Signal Recognition Particle (SRP) receptor
    NP_417921.1
    • cell division membrane protein

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3602750..3604243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417921.1 Signal Recognition Particle (SRP) receptor [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417921.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P10121
      Conserved Domains (3) summary
      smart00962
      Location:293493
      SRP54; SRP54-type protein, GTPase domain
      smart00963
      Location:207279
      SRP54_N; SRP54-type protein, helical bundle domain
      PRK10416
      Location:186497
      PRK10416; signal recognition particle-docking protein FtsY; Provisional
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