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    rnb ribonuclease II [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945864, updated on 25-Apr-2017
    Gene symbol
    rnb
    Gene description
    ribonuclease II
    Primary source
    EcoGene:EG11620
    Locus tag
    b1286
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1281; JW1279
    Summary
    Ribonuclease II (RNase II) is an exonuclease that cleaves RNA from the 3' end to produce ribonucleoside 5'-monophosphates. [More information is available at EcoCyc: EG11620].
    Sequence:
    NC_000913.3 (1346978..1348912, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cyclic-di-GMP phosphodiesterase; csgD regulator; modulator of RNase II stability Neighboring gene uncharacterized protein Neighboring gene putative oxidoreductase Neighboring gene enoyl-[acyl-carrier-protein] reductase, NADH-dependent

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    3'-5' exonuclease activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    3'-5'-exoribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA phosphodiester bond hydrolysis, exonucleolytic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    tRNA catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    exosome (RNase complex) IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Names
    ribonuclease II
    NP_415802.1
    • RNase II, mRNA degradation

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1346978..1348912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415802.1 ribonuclease II [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415802.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P30850
      Conserved Domains (4) summary
      PRK05054
      Location:1643
      PRK05054; exoribonuclease II; Provisional
      smart00955
      Location:189517
      RNB; This domain is the catalytic domain of ribonuclease II
      pfam00575
      Location:560635
      S1; S1 RNA binding domain
      pfam08206
      Location:2481
      OB_RNB; Ribonuclease B OB domain
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