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    CNE1 calnexin [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851241, updated on 9-Apr-2017
    Gene symbol
    CNE1
    Gene description
    calnexin
    Primary source
    SGD:S000000054
    Locus tag
    YAL058W
    Gene type
    protein coding
    RNA name
    calnexin
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    FUN48
    See CNE1 in Map Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_001133.9 (37464..38972)

    Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene (R,R)-butanediol dehydrogenase Neighboring gene Ecm1p Neighboring gene Gpb2p Neighboring gene ubiquitin-protein transferase activating protein PEX22

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    unfolded protein binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    unfolded protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein folding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ubiquitin-dependent ERAD pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    calnexin
    NP_009343.1
    • Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001133.9 Reference assembly

      Range
      37464..38972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178200.1NP_009343.1  TPA: calnexin [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_009343.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P27825
      Conserved Domains (1) summary
      pfam00262
      Location:33413
      Calreticulin; Calreticulin family
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