Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Jarid2 jumonji, AT rich interactive domain 2 [ Mus musculus (house mouse) ]

    Gene ID: 16468, updated on 5-Nov-2017
    Official Symbol
    Jarid2provided by MGI
    Official Full Name
    jumonji, AT rich interactive domain 2provided by MGI
    Primary source
    MGI:MGI:104813
    See related
    Ensembl:ENSMUSG00000038518 Vega:OTTMUSG00000037582
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Jmj; jumonji
    Orthologs
    Location:
    13 A5; 13 21.66 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (44729535..44921643)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (44826272..45016350)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34276 Neighboring gene predicted gene, 40931 Neighboring gene dystrobrevin binding protein 1 Neighboring gene predicted gene, 34409

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    covalent chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    liver development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cardiac muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cardiac muscle hypertrophy ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of histone methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of histone H3-K9 methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    spleen development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    stem cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    thymus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    colocalizes_with ESC/E(Z) complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with ESC/E(Z) complex ISO
    Inferred from Sequence Orthology
    more info
     
    histone methyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    protein Jumonji
    Names
    jumonji/ARID domain-containing protein 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205043.1NP_001191972.1  protein Jumonji

      See identical proteins and their annotated locations for NP_001191972.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC166074, AC170597
      Consensus CDS
      CCDS36646.1
      UniProtKB/Swiss-Prot
      Q62315
      Related
      ENSMUSP00000134205.1, OTTMUSP00000054205, ENSMUST00000173246.7, OTTMUST00000096894
      Conserved Domains (4) summary
      smart00501
      Location:621712
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:554595
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:9141029
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:11371190
      zf-C5HC2; C5HC2 zinc finger
    2. NM_001205044.1NP_001191973.1  protein Jumonji

      See identical proteins and their annotated locations for NP_001191973.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC166074, AC170597
      Consensus CDS
      CCDS36646.1
      UniProtKB/Swiss-Prot
      Q62315
      Related
      ENSMUSP00000134675.1, OTTMUSP00000054202, ENSMUST00000173704.7, OTTMUST00000096890
      Conserved Domains (4) summary
      smart00501
      Location:621712
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:554595
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:9141029
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:11371190
      zf-C5HC2; C5HC2 zinc finger
    3. NM_021878.3NP_068678.1  protein Jumonji

      See identical proteins and their annotated locations for NP_068678.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC166074, AC170597, BC052444
      Consensus CDS
      CCDS36646.1
      UniProtKB/Swiss-Prot
      Q62315
      Related
      ENSMUSP00000037774.7, OTTMUSP00000054203, ENSMUST00000044608.13, OTTMUST00000096891
      Conserved Domains (4) summary
      smart00501
      Location:621712
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:554595
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:9141029
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:11371190
      zf-C5HC2; C5HC2 zinc finger

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      44729535..44921643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516856.3XP_006516919.1  protein Jumonji isoform X1

      See identical proteins and their annotated locations for XP_006516919.1

      UniProtKB/Swiss-Prot
      Q62315
      Conserved Domains (4) summary
      smart00501
      Location:621712
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:554595
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:9141029
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:11371190
      zf-C5HC2; C5HC2 zinc finger
    2. XM_006516855.3XP_006516918.1  protein Jumonji isoform X1

      See identical proteins and their annotated locations for XP_006516918.1

      UniProtKB/Swiss-Prot
      Q62315
      Conserved Domains (4) summary
      smart00501
      Location:621712
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:554595
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:9141029
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:11371190
      zf-C5HC2; C5HC2 zinc finger
    3. XM_017315399.1XP_017170888.1  protein Jumonji isoform X3

      UniProtKB/Swiss-Prot
      Q62315
      Conserved Domains (4) summary
      smart00501
      Location:449540
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:382423
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:742857
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:9651018
      zf-C5HC2; C5HC2 zinc finger
    4. XM_006516859.2XP_006516922.1  protein Jumonji isoform X3

      See identical proteins and their annotated locations for XP_006516922.1

      UniProtKB/Swiss-Prot
      Q62315
      Conserved Domains (4) summary
      smart00501
      Location:449540
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:382423
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:742857
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:9651018
      zf-C5HC2; C5HC2 zinc finger
    5. XM_006516858.3XP_006516921.1  protein Jumonji isoform X2

      See identical proteins and their annotated locations for XP_006516921.1

      UniProtKB/Swiss-Prot
      Q62315
      Related
      ENSMUSP00000134630.1, OTTMUSP00000054208, ENSMUST00000173906.2, OTTMUST00000096901
      Conserved Domains (4) summary
      smart00501
      Location:583674
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:516557
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:876991
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:10991152
      zf-C5HC2; C5HC2 zinc finger
    6. XM_006516860.2XP_006516923.1  protein Jumonji isoform X3

      See identical proteins and their annotated locations for XP_006516923.1

      UniProtKB/Swiss-Prot
      Q62315
      Conserved Domains (4) summary
      smart00501
      Location:449540
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:382423
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:742857
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:9651018
      zf-C5HC2; C5HC2 zinc finger
    Support Center