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    thyA thymidylate synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949035, updated on 25-May-2017
    Gene symbol
    thyA
    Gene description
    thymidylate synthetase
    Primary source
    EcoGene:EG11002
    Locus tag
    b2827
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2823; JW2795
    Summary
    Thymidylate synthase (TS) catalytic mechanism order: [More information is available at EcoGene: EG11002]. Thymidylate synthase plays a key role in DNA synthesis. [More information is available at EcoCyc: EG11002].
    Sequence:
    NC_000913.3 (2964361..2965155, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative prepilin peptidase-dependent protein Neighboring gene DUF2509 family protein Neighboring gene putative prepilin peptidase-dependent protein Neighboring gene putative prepilin peptidase-dependent protein Neighboring gene phosphatidylglycerol-prolipoprotein diacylglyceryl transferase Neighboring gene PEP-protein phosphotransferase enzyme I; GAF domain containing protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    thymidylate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    dTMP biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2964361..2965155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417304.1 thymidylate synthetase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417304.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0A884
      Conserved Domains (1) summary
      PRK01827
      Location:1264
      thyA; thymidylate synthase; Reviewed
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