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    SEC53 phosphomannomutase SEC53 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850499, updated on 6-Aug-2017
    Gene symbol
    SEC53
    Gene description
    phosphomannomutase SEC53
    Primary source
    SGD:S000001849
    Locus tag
    YFL045C
    Gene type
    protein coding
    RNA name
    phosphomannomutase SEC53
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ALG4
    See SEC53 in Map Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (43628..44392, complement)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Rgd2p Neighboring gene Fmp32p Neighboring gene ubiquitin-specific protease OTU1 Neighboring gene Lam5p

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphomannomutase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphomannomutase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    GDP-mannose biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    GDP-mannose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    mannose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein targeting to ER IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    phosphomannomutase SEC53
    NP_116609.1
    • Phosphomannomutase; involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      43628..44392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179922.1NP_116609.1  TPA: phosphomannomutase SEC53 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116609.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07283
      Conserved Domains (2) summary
      COG0561
      Location:11245
      Cof; Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases [Coenzyme transport and metabolism, General function prediction only]
      pfam03332
      Location:36254
      PMM; Eukaryotic phosphomannomutase
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