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    Dcr-1 endoribonuclease Dicer-1 [ Apis mellifera (honey bee) ]

    Gene ID: 552127, updated on 10-Feb-2017
    Gene symbol
    Dcr-1
    Gene description
    endoribonuclease Dicer-1
    See related
    BEEBASE:GB44595
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Apis mellifera
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata; Apoidea; Apidae; Apis
    Also known as
    GB11966
    Location:
    chromosome: LG5
    Exon count:
    21
    Annotation release Status Assembly LG Location
    103 current Amel_4.5 (GCF_000002195.4) LG5 NC_007074.3 (10264835..10273957)

    Linkage Group LG5 - NC_007074.3Genomic Context describing neighboring genes Neighboring gene tyrosine-protein kinase hopscotch Neighboring gene uncharacterized LOC552106 Neighboring gene nitrogen permease regulator 3-like protein Neighboring gene uncharacterized LOC409510

    Genomic Sequence:
    NC_007074.3 Chromosome LG5 Reference Amel_4.5 Primary Assembly

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Preferred Names
    endoribonuclease Dicer-1
    Names
    dicer 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123013.2NP_001116485.2  endoribonuclease Dicer-1

      Status: PROVISIONAL

      Source sequence(s)
      AADG06005424
      UniProtKB/TrEMBL
      A0A088A073
      Conserved Domains (9) summary
      smart00535
      Location:14181508
      RIBOc; Ribonuclease III family
      COG0571
      Location:16961942
      Rnc; dsRNA-specific ribonuclease [Transcription]
      cd00046
      Location:30171
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00048
      Location:19051941
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      cd00593
      Location:17101874
      RIBOc; RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in ...
      cd02843
      Location:8861007
      PAZ_dicer_like; PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named ...
      cd15903
      Location:239340
      Dicer_PBD; Partner-binding domain of the endoribonuclease Dicer
      pfam00271
      Location:464547
      Helicase_C; Helicase conserved C-terminal domain
      pfam03368
      Location:624710
      Dicer_dimer; Dicer dimerization domain

    RefSeqs of Annotated Genomes: Apis mellifera Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Amel_4.5 Primary Assembly

    Genomic

    1. NC_007074.3 Reference Amel_4.5 Primary Assembly

      Range
      10264835..10273957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016912057.1XP_016767546.1  endoribonuclease Dicer-1 isoform X1

      UniProtKB/TrEMBL
      A0A088A073
      Conserved Domains (9) summary
      smart00535
      Location:14181508
      RIBOc; Ribonuclease III family
      COG0571
      Location:16961942
      Rnc; dsRNA-specific ribonuclease [Transcription]
      cd00046
      Location:30171
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00048
      Location:19051941
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      cd00593
      Location:17101874
      RIBOc; RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in ...
      cd02843
      Location:8861007
      PAZ_dicer_like; PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named ...
      cd15903
      Location:239340
      Dicer_PBD; Partner-binding domain of the endoribonuclease Dicer
      pfam00271
      Location:464547
      Helicase_C; Helicase conserved C-terminal domain
      pfam03368
      Location:624710
      Dicer_dimer; Dicer dimerization domain
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