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    p38b p38b MAP kinase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34780, updated on 9-Jul-2017
    Official Symbol
    p38bprovided by FlyBase
    Official Full Name
    p38b MAP kinaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024846
    Locus tag
    Dmel_CG7393
    Gene type
    protein coding
    RNA name
    p38b MAP kinase
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    186F5S; anon-sts23; BG:DS00797.3; CG7393; D-p38; D-p38 MAPK; D-p38b; Dm p38b; Dmel\CG7393; Dmp38b; Dp38; dp38b; Dp38b; ESTS:186F5S; MAPK; Mpk34C; p38; P38; p38 beta; p38 MAPK; p38B; p38beta; p38Kb
    Location:
    34D1-34D1
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13780689..13782611)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13780689..13782611)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene CG43376 gene product from transcript CG43376-RA Neighboring gene CG9008 gene product from transcript CG9008-RA Neighboring gene ncRNA Neighboring gene CG16890 gene product from transcript CG16890-RD Neighboring gene CG31731 gene product from transcript CG31731-RB Neighboring gene ncRNA Neighboring gene CG16863 gene product from transcript CG16863-RA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    MAP kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    MAP kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    SAP kinase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein serine/threonine kinase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    MAPK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    MAPK cascade NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cellular response to arsenic-containing substance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to cadmium ion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to reactive oxygen species IDA
    Inferred from Direct Assay
    more info
    PubMed 
    circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    imaginal disc-derived wing morphogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    paracrine signaling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cell size IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cell size IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of protein phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein phosphorylation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    reactive oxygen species metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of BMP signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of adult chitin-containing cuticle pigmentation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of glucose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of innate immune response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of terminal button organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to bacterium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to heat IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to hydrogen peroxide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to starvation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    CG7393 gene product from transcript CG7393-RA
    Names
    CG7393-PA
    p38 MAP kinase
    p38 mitogen-activated protein kinase
    p38b MAP kinase
    p38b-PA
    stress-activated p38b MAP kinase
    NP_477361.1

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13780689..13782611
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058013.5NP_477361.1  p38b MAP kinase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477361.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61443
      Related
      FBpp0080111, FBtr0080534
      Conserved Domains (2) summary
      cd07851
      Location:8353
      STKc_p38; Catalytic domain of the Serine/Threonine Kinase, p38 Mitogen-Activated Protein Kinase
      smart00220
      Location:24311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
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