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    PSG11 pregnancy specific beta-1-glycoprotein 11 [ Homo sapiens (human) ]

    Gene ID: 5680, updated on 24-Sep-2016
    Official Symbol
    PSG11provided by HGNC
    Official Full Name
    pregnancy specific beta-1-glycoprotein 11provided by HGNC
    Primary source
    HGNC:HGNC:9516
    See related
    Ensembl:ENSG00000243130 HPRD:08898; MIM:176401; Vega:OTTHUMG00000151546
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PSG13; PSG14; PSBG-11; PSBG-13
    Summary
    The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
    Orthologs
    Location:
    19q13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 19 NC_000019.10 (43007657..43026479, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (43511809..43530658, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) Neighboring gene carcinoembryonic antigen related cell adhesion molecule pseudogene 7 Neighboring gene carcinoembryonic antigen related cell adhesion molecule pseudogene 8 Neighboring gene pregnancy specific beta-1-glycoprotein 2

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Potential readthrough

    Included gene: PSG6

    Clone Names

    • MGC22484

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    female pregnancy TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    pregnancy-specific beta-1-glycoprotein 11
    Names
    PS-beta-G-11
    PS-beta-G-13
    pregnancy-specific beta-1-glycoprotein 13

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113410.1NP_001106881.1  pregnancy-specific beta-1-glycoprotein 11 isoform 2

      See identical proteins and their annotated locations for NP_001106881.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Both variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AC005947, BC020711, BE767872, BG619770, R66665
      Consensus CDS
      CCDS12615.2
      UniProtKB/Swiss-Prot
      Q9UQ72
      Related
      ENSP00000385427, OTTHUMP00000200194, ENST00000403486, OTTHUMT00000323082
      Conserved Domains (3) summary
      smart00410
      Location:124196
      IG_like; Immunoglobulin like
      pfam13895
      Location:120198
      Ig_2; Immunoglobulin domain
      cl11960
      Location:26114
      Ig; Immunoglobulin domain
    2. NM_002785.2NP_002776.3  pregnancy-specific beta-1-glycoprotein 11 isoform 1 precursor

      See identical proteins and their annotated locations for NP_002776.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC005947, BC020711, BE767872, BF084984, BG619770, R66665
      Consensus CDS
      CCDS12614.2
      UniProtKB/Swiss-Prot
      Q9UQ72
      Related
      ENSP00000319140, OTTHUMP00000200192, ENST00000320078, OTTHUMT00000323079
      Conserved Domains (4) summary
      cd05774
      Location:36138
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00410
      Location:246318
      IG_like; Immunoglobulin like
      pfam13895
      Location:242320
      Ig_2; Immunoglobulin domain
      cl11960
      Location:148236
      Ig; Immunoglobulin domain
    3. NM_203287.1NP_976032.2  pregnancy-specific beta-1-glycoprotein 11 isoform 2

      See identical proteins and their annotated locations for NP_976032.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Both variants 2 and 3 encode the same isoform.
      Source sequence(s)
      AC005947, BC020711, BG619770, R66665
      Consensus CDS
      CCDS12615.2
      UniProtKB/Swiss-Prot
      Q9UQ72
      Related
      ENSP00000304913, OTTHUMP00000270381, ENST00000306322, OTTHUMT00000464115
      Conserved Domains (3) summary
      smart00410
      Location:124196
      IG_like; Immunoglobulin like
      pfam13895
      Location:120198
      Ig_2; Immunoglobulin domain
      cl11960
      Location:26114
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p7 Primary Assembly

      Range
      43007657..43026479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018930.2 Alternate CHM1_1.1

      Range
      43513374..43532200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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