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    unc-6 Netrin unc-6 [ Caenorhabditis elegans ]

    Gene ID: 180961, updated on 8-May-2017
    Gene symbol
    unc-6
    Gene description
    Netrin unc-6
    Primary source
    WormBase:WBGene00006746
    Locus tag
    CELE_F41C6.1
    Gene type
    protein coding
    RNA name
    Netrin unc-6
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See unc-6 in Map Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (6889740..6896628)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    axon extension IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    axon guidance IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dendrite development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    dorsal/ventral axon guidance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    dorsal/ventral axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gonad morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    gonad morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    interneuron axon guidance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    interneuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    mesodermal cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode male tail tip morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    netrin-activated signaling pathway IC
    Inferred by Curator
    more info
    PubMed 
    neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    regulation of cell migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basement membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basement membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    proteinaceous extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Netrin unc-6
    NP_509165.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6889740..6896628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076764.3NP_509165.1  Netrin unc-6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34710
      Conserved Domains (4) summary
      smart00136
      Location:41289
      LamNT; Laminin N-terminal domain (domain VI)
      cd00055
      Location:290333
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03579
      Location:490604
      NTR_netrin-1_like; NTR domain, Netrin-1-like subfamily; The C-terminal NTR domain of netrins is also called domain C in the context of C. elegans netrin UNC-6. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration ...
      pfam00053
      Location:410453
      Laminin_EGF; Laminin EGF domain
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