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    Gps2 G protein pathway suppressor 2 [ Mus musculus (house mouse) ]

    Gene ID: 56310, updated on 7-May-2017
    Official Symbol
    Gps2provided by MGI
    Official Full Name
    G protein pathway suppressor 2provided by MGI
    Primary source
    MGI:MGI:1891751
    See related
    Ensembl:ENSMUSG00000023170 Vega:OTTMUSG00000006026
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI505953
    Orthologs
    Location:
    11; 11 B3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (69913978..69917056)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69727694..69730093)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2810408A11 gene Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene eukaryotic translation initiation factor 5A Neighboring gene Y box protein 2 Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 4

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • HTLV-I infection, organism-specific biosystem (from KEGG)
      HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    • HTLV-I infection, conserved biosystem (from KEGG)
      HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of JNK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcriptional repressor complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    G protein pathway suppressor 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019726.3NP_062700.2  G protein pathway suppressor 2

      See identical proteins and their annotated locations for NP_062700.2

      Status: PROVISIONAL

      Source sequence(s)
      AL596185
      Consensus CDS
      CCDS24922.1
      UniProtKB/TrEMBL
      Q921N8
      Related
      ENSMUSP00000054072.5, OTTMUSP00000006272, ENSMUST00000057884.5, OTTMUST00000013528
      Conserved Domains (2) summary
      pfam13863
      Location:4189
      DUF4200; Domain of unknown function (DUF4200)
      pfam15991
      Location:5292
      G_path_suppress; G-protein pathway suppressor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      69913978..69917056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314684.1XP_017170173.1  G protein pathway suppressor 2 isoform X1

    2. XM_006533787.2XP_006533850.1  G protein pathway suppressor 2 isoform X4

      See identical proteins and their annotated locations for XP_006533850.1

      UniProtKB/TrEMBL
      Q921N8
      Related
      ENSMUSP00000112062.1, ENSMUST00000116358.7
      Conserved Domains (2) summary
      pfam13863
      Location:4189
      DUF4200; Domain of unknown function (DUF4200)
      pfam15991
      Location:5292
      G_path_suppress; G-protein pathway suppressor
    3. XM_006533785.2XP_006533848.1  G protein pathway suppressor 2 isoform X2

      See identical proteins and their annotated locations for XP_006533848.1

      Conserved Domains (2) summary
      pfam13863
      Location:4189
      DUF4200; Domain of unknown function (DUF4200)
      pfam15991
      Location:5292
      G_path_suppress; G-protein pathway suppressor
    4. XM_017314685.1XP_017170174.1  G protein pathway suppressor 2 isoform X3

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187026.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      18720..21119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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