Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Dgat1 diacylglycerol O-acyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 13350, updated on 26-Nov-2016
    Official Symbol
    Dgat1provided by MGI
    Official Full Name
    diacylglycerol O-acyltransferase 1provided by MGI
    Primary source
    MGI:MGI:1333825
    See related
    Ensembl:ENSMUSG00000022555 Vega:OTTMUSG00000034893
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ARAT; Dgat; C75990; D15Ertd23e
    Orthologs
    Location:
    15 D3; 15 35.99 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (76502015..76512021, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (76332445..76342248, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene block of proliferation 1 Neighboring gene scleraxis Neighboring gene heat shock factor 1 Neighboring gene uncharacterized LOC108168260 Neighboring gene scratch family zinc finger 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    2-acylglycerol O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    diacylglycerol O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    diacylglycerol O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    diacylglycerol binding ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    retinol O-fatty-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    diacylglycerol metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    glycerolipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    insulin secretion ISO
    Inferred from Sequence Orthology
    more info
     
    ketone body metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    lipid storage IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    long-chain fatty-acyl-CoA metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of fatty acid oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of hepatic stellate cell activation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of triglyceride biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of eating behavior ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of intestinal lipid absorption ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of vitamin A metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    triglyceride biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    triglyceride biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    very-low-density lipoprotein particle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular membrane-bounded organelle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    diacylglycerol O-acyltransferase 1
    Names
    acyl-CoA retinol O-fatty-acyltransferase
    diacylglycerol acyltransferase 1
    diglyceride acyltransferase
    retinol O-fatty-acyltransferase
    NP_034176.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010046.2NP_034176.1  diacylglycerol O-acyltransferase 1

      See identical proteins and their annotated locations for NP_034176.1

      Status: PROVISIONAL

      Source sequence(s)
      BC003717
      Consensus CDS
      CCDS27573.1
      UniProtKB/Swiss-Prot
      Q9Z2A7
      UniProtKB/TrEMBL
      Q54AA6
      Related
      ENSMUSP00000023214, OTTMUSP00000048375, ENSMUST00000023214, OTTMUST00000088696
      Conserved Domains (1) summary
      cl00738
      Location:79483
      MBOAT; MBOAT, membrane-bound O-acyltransferase family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      76502015..76512021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520405.2XP_006520468.1  

      Conserved Domains (1) summary
      cl00738
      Location:8418
      MBOAT; MBOAT, membrane-bound O-acyltransferase family
    2. XM_017316426.1XP_017171915.1  

    RNA

    1. XR_383978.3 RNA Sequence

    Support Center