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    Wdr74 WD repeat domain 74 [ Mus musculus (house mouse) ]

    Gene ID: 107071, updated on 25-May-2017
    Official Symbol
    Wdr74provided by MGI
    Official Full Name
    WD repeat domain 74provided by MGI
    Primary source
    MGI:MGI:2147427
    See related
    Ensembl:ENSMUSG00000042729 Ensembl:ENSMUSG00000110423 Vega:OTTMUSG00000060351; Vega:OTTMUSG00000060352
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA407588; 5730436H21Rik
    Orthologs
    Location:
    19; 19 A
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (8735804..8740624)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (8810329..8815114)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Neighboring gene small nucleolar RNA host gene 1 Neighboring gene small nucleolar RNA, C/D box 22 Neighboring gene RIKEN cDNA 1700092M07 gene Neighboring gene syntaxin 5A Neighboring gene microRNA 6992

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    RNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blastocyst formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    WD repeat-containing protein 74

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134139.1NP_598900.1  WD repeat-containing protein 74

      See identical proteins and their annotated locations for NP_598900.1

      Status: PROVISIONAL

      Source sequence(s)
      BC019968
      Consensus CDS
      CCDS29541.1
      UniProtKB/Swiss-Prot
      Q8VCG3
      Related
      ENSMUSP00000043315.9, OTTMUSP00000076836, ENSMUST00000049424.10, OTTMUST00000147684
      Conserved Domains (3) summary
      COG2319
      Location:42295
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:91127
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:45302
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      8735804..8740624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526554.3XP_006526617.1  WD repeat-containing protein 74 isoform X1

      See identical proteins and their annotated locations for XP_006526617.1

      UniProtKB/TrEMBL
      Q8R3V4
      Conserved Domains (3) summary
      COG2319
      Location:9160
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:5690
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:7167
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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