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    MIR374A microRNA 374a [ Homo sapiens (human) ]

    Gene ID: 442919, updated on 3-Sep-2017
    Official Symbol
    MIR374Aprovided by HGNC
    Official Full Name
    microRNA 374aprovided by HGNC
    Primary source
    See related
    Ensembl:ENSG00000199168 miRBase:MI0000782
    Gene type
    RefSeq status
    Homo sapiens
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIRN374; MIRN374A; mir-374a; hsa-mir-374
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Exon count:
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) X NC_000023.11 (74287286..74287357, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (73507121..73507192, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene FTX transcript, XIST regulator (non-protein coding) Neighboring gene RNA, 7SL, cytoplasmic 648, pseudogene Neighboring gene microRNA 545 Neighboring gene zinc finger CCHC-type containing 13 Neighboring gene NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


    1. NR_030785.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly


    1. NC_000023.11 Reference GRCh38.p7 Primary Assembly

      74287286..74287357 complement
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1


    1. NC_018934.2 Alternate CHM1_1.1

      73400117..73400188 complement
      GenBank, FASTA, Sequence Viewer (Graphics)
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