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    Trpv3 transient receptor potential cation channel, subfamily V, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497948, updated on 12-Mar-2017
    Official Symbol
    Trpv3provided by RGD
    Official Full Name
    transient receptor potential cation channel, subfamily V, member 3provided by RGD
    Primary source
    RGD:1564531
    See related
    Ensembl:ENSRNOG00000019606
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    Location:
    10q24
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (59829755..59863780)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (59570474..59600221)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene cystinosin, lysosomal cystine transporter Neighboring gene sedoheptulokinase Neighboring gene transient receptor potential cation channel, subfamily V, member 1 Neighboring gene aspartoacylase Neighboring gene spermatogenesis associated 22 Neighboring gene olfactory receptor 1466

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cation channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of hair cycle IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of hair cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of calcium ion import IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to heat IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to temperature stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    receptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    transient receptor potential cation channel subfamily V member 3
    Names
    heat sensitive channel TRPV3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025757.2NP_001020928.2  transient receptor potential cation channel subfamily V member 3

      See identical proteins and their annotated locations for NP_001020928.2

      Status: VALIDATED

      Source sequence(s)
      AC126839
      UniProtKB/TrEMBL
      E9PU00
      Related
      ENSRNOP00000026596, ENSRNOT00000026596
      Conserved Domains (5) summary
      cd00204
      Location:213361
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:468689
      Ion_trans; Ion transport protein
      pfam12796
      Location:172293
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:214245
      ANK; ANK repeat [structural motif]
      cl11542
      Location:490609
      EcsB; Bacterial ABC transporter protein EcsB

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      59829755..59863780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597462.1XP_017452951.1  transient receptor potential cation channel subfamily V member 3 isoform X3

    2. XM_017597461.1XP_017452950.1  transient receptor potential cation channel subfamily V member 3 isoform X3

    3. XM_017597460.1XP_017452949.1  transient receptor potential cation channel subfamily V member 3 isoform X3

    4. XM_008767860.2XP_008766082.1  transient receptor potential cation channel subfamily V member 3 isoform X5

      Conserved Domains (5) summary
      cd00204
      Location:213361
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00520
      Location:468689
      Ion_trans; Ion transport protein
      pfam12796
      Location:172293
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:214245
      ANK; ANK repeat [structural motif]
      cl11542
      Location:490609
      EcsB; Bacterial ABC transporter protein EcsB
    5. XM_017597458.1XP_017452947.1  transient receptor potential cation channel subfamily V member 3 isoform X1

    6. XM_017597459.1XP_017452948.1  transient receptor potential cation channel subfamily V member 3 isoform X2

    7. XM_017597463.1XP_017452952.1  transient receptor potential cation channel subfamily V member 3 isoform X4

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      57006489..57036234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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