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    Lcn2 lipocalin 2 [ Mus musculus (house mouse) ]

    Gene ID: 16819, updated on 25-Jun-2017
    Official Symbol
    Lcn2provided by MGI
    Official Full Name
    lipocalin 2provided by MGI
    Primary source
    MGI:MGI:96757
    See related
    Ensembl:ENSMUSG00000026822 Vega:OTTMUSG00000012958
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NRL; 24p3; Sip24; AW212229
    Orthologs
    Location:
    2 B; 2 22.09 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (32384637..32387739, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (32240157..32243259, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene CDKN1A interacting zinc finger protein 1 Neighboring gene RIKEN cDNA 1110008P14 gene Neighboring gene prostaglandin E synthase 2 Neighboring gene 60S ribosomal protein L15-like

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    iron ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    small molecule binding IEA
    Inferred from Electronic Annotation
    more info
     
    transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hydrogen peroxide ISO
    Inferred from Sequence Orthology
    more info
     
    extrinsic apoptotic signaling pathway in absence of ligand IDA
    Inferred from Direct Assay
    more info
    PubMed 
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell projection organization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    protein homotrimerization ISO
    Inferred from Sequence Orthology
    more info
     
    response to drug ISO
    Inferred from Sequence Orthology
    more info
     
    response to herbicide ISO
    Inferred from Sequence Orthology
    more info
     
    response to virus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    siderophore transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    siderophore transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    neutrophil gelatinase-associated lipocalin
    Names
    SV-40-induced 24P3 protein
    neu-related lipocalin
    p25
    secreted inducible protein 24
    siderocalin LCN2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008491.1NP_032517.1  neutrophil gelatinase-associated lipocalin precursor

      See identical proteins and their annotated locations for NP_032517.1

      Status: PROVISIONAL

      Source sequence(s)
      X14607
      Consensus CDS
      CCDS15913.1
      UniProtKB/Swiss-Prot
      P11672
      Related
      ENSMUSP00000053962.8, OTTMUSP00000013951, ENSMUST00000050785.13, OTTMUST00000031183
      Conserved Domains (1) summary
      pfam00061
      Location:49195
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      32384637..32387739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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