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    lacY lactose permease [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949083, updated on 19-Nov-2016
    Gene symbol
    lacY
    Gene description
    lactose permease
    Primary source
    EcoGene:EG10526
    Locus tag
    b0343
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0340; JW0334
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG10526]. The lactose permease LacY is a lactose/proton symporter, responsible for the uptake of lactose and other galactosides. [More information is available at EcoCyc: EG10526].
    Sequence:
    NC_000913.3 (361926..363179, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative cyanate transporter Neighboring gene thiogalactoside acetyltransferase Neighboring gene beta-D-galactosidase Neighboring gene lactose-inducible lac operon transcriptional repressor

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    lactose binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lactose:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lactose:proton symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sugar:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    carbohydrate transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lactose transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    proton transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    lactose permease
    NP_414877.1
    • galactoside permease (lactose permease, M protein) (MFS family)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      361926..363179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414877.1 lactose permease [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414877.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P02920
      Conserved Domains (2) summary
      pfam01306
      Location:1413
      LacY_symp; LacY proton/sugar symporter
      cd06174
      Location:23398
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
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