Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    SUP35 translation termination factor GTPase eRF3 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851752, updated on 9-Apr-2017
    Gene symbol
    SUP35
    Gene description
    translation termination factor GTPase eRF3
    Primary source
    SGD:S000002579
    Locus tag
    YDR172W
    Gene type
    protein coding
    RNA name
    translation termination factor GTPase eRF3
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GST1; PNM2; SAL3; SUF12; SUP2; SUP36
    See SUP35 in Map Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (808324..810381)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene gag protein Neighboring gene heat shock protein HSP42 Neighboring gene inositol polyphosphate multikinase Neighboring gene Hmo1p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    translation release factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translation release factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cytoplasmic translational termination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    translational termination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translational termination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translation release factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    translation termination factor GTPase eRF3
    NP_010457.3
    • Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)]

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      808324..810381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180479.3NP_010457.3  TPA: translation termination factor GTPase eRF3 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_010457.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P05453
      Conserved Domains (4) summary
      cd01883
      Location:262479
      EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
      COG5256
      Location:254685
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      cd04089
      Location:489571
      eRF3_II; Domain II of the eukaryotic class II release factor
      cd03704
      Location:577683
      eRF3_C_III; C-terminal domain of eRF3
    Support Center