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    AZGP1 alpha-2-glycoprotein 1, zinc-binding [ Homo sapiens (human) ]

    Gene ID: 563, updated on 8-Oct-2017
    Official Symbol
    AZGP1provided by HGNC
    Official Full Name
    alpha-2-glycoprotein 1, zinc-bindingprovided by HGNC
    Primary source
    HGNC:HGNC:910
    See related
    Ensembl:ENSG00000160862 MIM:194460; Vega:OTTHUMG00000023066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZAG; ZA2G
    Orthologs
    Location:
    7q22.1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 7 NC_000007.14 (99966727..99976112, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (99564350..99573735, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 4 Neighboring gene uncharacterized LOC101927610 Neighboring gene gap junction protein gamma 3 Neighboring gene alpha-2-glycoprotein 1, zinc-binding pseudogene 1 Neighboring gene gap junction protein gamma 3 pseudogene

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein transmembrane transporter activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    ribonuclease activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA phosphodiester bond hydrolysis IEA
    Inferred from Electronic Annotation
    more info
     
    cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    detection of chemical stimulus involved in sensory perception of bitter taste IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell proliferation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    retina homeostasis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    transmembrane transport TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region NAS
    Non-traceable Author Statement
    more info
    PubMed 
    extracellular region TAS
    Traceable Author Statement
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    zinc-alpha-2-glycoprotein
    Names
    Alpha-2-glycoprotein, zinc
    Zn-alpha2-glycoprotein
    testicular tissue protein Li 227
    zn-alpha-2-GP
    zn-alpha-2-glycoprotein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001185.3NP_001176.1  zinc-alpha-2-glycoprotein precursor

      See identical proteins and their annotated locations for NP_001176.1

      Status: VALIDATED

      Source sequence(s)
      AW015837, BC005306, BC033830, CB148270
      Consensus CDS
      CCDS5680.1
      UniProtKB/Swiss-Prot
      P25311
      UniProtKB/TrEMBL
      A0A140VK00
      Related
      ENSP00000292401.4, OTTHUMP00000024684, ENST00000292401.8, OTTHUMT00000059387
      Conserved Domains (2) summary
      cd07698
      Location:205296
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:26201
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p7 Primary Assembly

      Range
      99966727..99976112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018918.2 Alternate CHM1_1.1

      Range
      99494515..99503901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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