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    HSP82 Hsp90 family chaperone HSP82 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855836, updated on 14-Oct-2017
    Gene symbol
    HSP82
    Gene description
    Hsp90 family chaperone HSP82
    Primary source
    SGD:S000006161
    Locus tag
    YPL240C
    Gene type
    protein coding
    RNA name
    Hsp90 family chaperone HSP82
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HSP90
    See HSP82 in Map Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (96496..98625, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Iqg1p Neighboring gene GTPase-activating protein CIN2 Neighboring gene Yar1p Neighboring gene translation initiation factor eIF2 subunit beta

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity, coupled IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATPase activity, coupled IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    'de novo' protein folding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    'de novo' protein folding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    box C/D snoRNP assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of telomere maintenance via telomerase IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of telomere maintenance via telomerase IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    proteasome assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    proteasome assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein refolding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein targeting to mitochondrion IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to stress IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Hsp90 family chaperone HSP82
    NP_015084.1
    • Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      96496..98625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184054.1NP_015084.1  TPA: Hsp90 family chaperone HSP82 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015084.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02829
      Conserved Domains (1) summary
      cl27733
      Location:3709
      HSP90; Hsp90 protein
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