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    Arc activity regulated cytoskeletal-associated protein [ Mus musculus (house mouse) ]

    Gene ID: 11838, updated on 4-Sep-2016
    Official Symbol
    Arcprovided by MGI
    Official Full Name
    activity regulated cytoskeletal-associated proteinprovided by MGI
    Primary source
    MGI:MGI:88067
    See related
    Ensembl:ENSMUSG00000022602 Vega:OTTMUSG00000016386
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mArc; Arc3.1; C86064; arg3.1
    Orthologs
    Location:
    15 D3; 15 34.25 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (74669081..74672570, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (74499513..74503000, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor B1 Neighboring gene maestro heat-like repeat family member 4 Neighboring gene predicted gene, 32994 Neighboring gene RIKEN cDNA 4933427E11 gene Neighboring gene jerky Neighboring gene prostate stem cell antigen

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Amphetamine addiction, organism-specific biosystem (from KEGG)
      Amphetamine addiction, organism-specific biosystemAmphetamine is a psychostimulant drug that exerts persistent addictive effects. Most addictive drugs increase extracellular concentrations of dopamine (DA) in nucleus accumbens (NAc) and medial prefr...
    • Amphetamine addiction, conserved biosystem (from KEGG)
      Amphetamine addiction, conserved biosystemAmphetamine is a psychostimulant drug that exerts persistent addictive effects. Most addictive drugs increase extracellular concentrations of dopamine (DA) in nucleus accumbens (NAc) and medial prefr...
    • Serotonin and anxiety, organism-specific biosystem (from WikiPathways)
      Serotonin and anxiety, organism-specific biosystemBenekareddy et al observed the phenomenon that rats who were maternally separated show increased levels of induced anxiety-related behaviour during adulthood. Type 2 serotonin receptors have been imp...
    • Serotonin and anxiety-related events, organism-specific biosystem (from WikiPathways)
      Serotonin and anxiety-related events, organism-specific biosystem
      Serotonin and anxiety-related events
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding TAS
    Traceable Author Statement
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    anterior/posterior pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    endoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton TAS
    Traceable Author Statement
    more info
    PubMed 
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    activity-regulated cytoskeleton-associated protein
    Names
    ARC/ARG3.1
    activity-regulated gene 3.1 protein homolog
    arc

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001276684.1NP_001263613.1  activity-regulated cytoskeleton-associated protein

      See identical proteins and their annotated locations for NP_001263613.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC118022, AK157822
      Consensus CDS
      CCDS37102.1
      UniProtKB/Swiss-Prot
      Q9WV31
      Related
      ENSMUSP00000105636, OTTMUSP00000017628, ENSMUST00000110009, OTTMUST00000039452
    2. NM_018790.3NP_061260.1  activity-regulated cytoskeleton-associated protein

      See identical proteins and their annotated locations for NP_061260.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC118022, AF162777
      Consensus CDS
      CCDS37102.1
      UniProtKB/Swiss-Prot
      Q9WV31
      Related
      ENSMUSP00000023268, OTTMUSP00000021864, ENSMUST00000023268, OTTMUST00000047955

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      74669081..74672570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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