Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Cracr2b calcium release activated channel regulator 2B [ Mus musculus (house mouse) ]

    Gene ID: 213573, updated on 25-May-2017
    Official Symbol
    Cracr2bprovided by MGI
    Official Full Name
    calcium release activated channel regulator 2Bprovided by MGI
    Primary source
    MGI:MGI:2446129
    See related
    Ensembl:ENSMUSG00000048200 Vega:OTTMUSG00000036654
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Efcab4; Cracr2a; Efcab4a; BC026645; 6330520A15Rik
    Orthologs
    Location:
    7; 7 F5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (141460870..141466613)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (148646993..148652501)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein, large P2 Neighboring gene small nucleolar RNA, H/ACA box 52 Neighboring gene patatin-like phospholipase domain containing 2 Neighboring gene predicted gene 10575 Neighboring gene CD151 antigen Neighboring gene polymerase (RNA) II (DNA directed) polypeptide L

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of store-operated calcium entry IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    store-operated calcium entry ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    EF-hand calcium-binding domain-containing protein 4A
    Names
    EF-hand calcium binding domain 4A

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025103.2NP_001020274.2  EF-hand calcium-binding domain-containing protein 4A

      See identical proteins and their annotated locations for NP_001020274.2

      Status: VALIDATED

      Source sequence(s)
      BC048916
      Consensus CDS
      CCDS22016.1
      UniProtKB/Swiss-Prot
      Q80ZJ8
      Related
      ENSMUSP00000055899.5, OTTMUSP00000052192, ENSMUST00000053670.11, OTTMUST00000093930
      Conserved Domains (2) summary
      cd00051
      Location:3288
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:3388
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      141460870..141466613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006536173.3XP_006536236.1  EF-hand calcium-binding domain-containing protein 4A isoform X2

      Conserved Domains (1) summary
      pfam13094
      Location:335410
      CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
    2. XM_006536172.3XP_006536235.1  EF-hand calcium-binding domain-containing protein 4A isoform X1

      Conserved Domains (1) summary
      pfam11068
      Location:303406
      YlqD; YlqD protein
    3. XM_006536174.2XP_006536237.1  EF-hand calcium-binding domain-containing protein 4A isoform X3

      See identical proteins and their annotated locations for XP_006536237.1

      UniProtKB/Swiss-Prot
      Q80ZJ8
      Conserved Domains (2) summary
      cd00051
      Location:3288
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:3388
      EF-hand_7; EF-hand domain pair
    Support Center