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    Slc5a1 solute carrier family 5 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25552, updated on 13-Mar-2018
    Official Symbol
    Slc5a1provided by RGD
    Official Full Name
    solute carrier family 5 member 1provided by RGD
    Primary source
    RGD:3713
    See related
    Ensembl:ENSRNOG00000017775
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    SGLT1; SGLT1a
    Summary
    catalyzes sodium dependent glucose transport; plays a role in sugar absorption in the small intestine and reabsorption of sugars in the kidney [RGD, Feb 2006]
    Annotation information
    Annotation category: suggests misassembly
    Expression
    Biased expression in Kidney (RPKM 121.6) and Lung (RPKM 51.7) See more
    Orthologs
    Location:
    14q21
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (82910448..82975303, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 14 NC_005113.3 (83595212..83660531, complement)

    Chromosome 14 - NC_005113.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352783 Neighboring gene spondin-2-like Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Neighboring gene DEP domain containing 5

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC93553

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    glucose transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    glucose:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    glucose:sodium symporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glucose:sodium symporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    glucose:sodium symporter activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    glucose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    glucose transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    glucose transmembrane transport TAS
    Traceable Author Statement
    more info
    PubMed 
    intestinal D-glucose absorption TAS
    Traceable Author Statement
    more info
    PubMed 
    intestinal absorption ISO
    Inferred from Sequence Orthology
    more info
     
    intestinal absorption TAS
    Traceable Author Statement
    more info
    PubMed 
    metanephros development ISO
    Inferred from Sequence Orthology
    more info
     
    sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    brush border ISO
    Inferred from Sequence Orthology
    more info
     
    brush border membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    sodium/glucose cotransporter 1
    Names
    Na(+)/glucose cotransporter 1
    Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)
    high affinity sodium-glucose cotransporter
    solute carrier family 5 (sodium/glucose cotransporter), member 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013033.2NP_037165.1  sodium/glucose cotransporter 1

      See identical proteins and their annotated locations for NP_037165.1

      Status: PROVISIONAL

      Source sequence(s)
      D16101
      UniProtKB/Swiss-Prot
      P53790
      Related
      ENSRNOP00000024165.5, ENSRNOT00000024165.6
      Conserved Domains (1) summary
      cl00456
      Location:27665
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005113.4 Reference Rnor_6.0 Primary Assembly

      Range
      82910448..82975303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000082.1 Alternate Rn_Celera

      Range
      76469843..76534501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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