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    Cd19 CD19 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12478, updated on 5-Nov-2017
    Official Symbol
    Cd19provided by MGI
    Official Full Name
    CD19 antigenprovided by MGI
    Primary source
    MGI:MGI:88319
    See related
    Ensembl:ENSMUSG00000030724 Vega:OTTMUSG00000058214
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW495831
    Orthologs
    Location:
    7 F3; 7 69.01 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (126408448..126415143, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133551962..133558384, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene spinster homolog 1 Neighboring gene nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein Neighboring gene rabaptin, RAB GTPase binding effector protein 2 Neighboring gene ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Neighboring gene SH2B adaptor protein 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signal transducer activity, downstream of receptor IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    B cell receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular defense response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of release of sequestered calcium ion into cytosol IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    B-lymphocyte antigen CD19
    Names
    differentiation antigen CD19

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357091.1NP_001344020.1  B-lymphocyte antigen CD19 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Conserved Domains (2) summary
      smart00410
      Location:183263
      IG_like; Immunoglobulin like
      cd04979
      Location:21118
      Ig_Semaphorin_C; Immunoglobulin (Ig)-like domain of semaphorin
    2. NM_009844.2NP_033974.2  B-lymphocyte antigen CD19 isoform 1 precursor

      See identical proteins and their annotated locations for NP_033974.2

      Status: VALIDATED

      Source sequence(s)
      AK163608, BE686865, BY234629
      Consensus CDS
      CCDS21828.1
      UniProtKB/Swiss-Prot
      P25918
      UniProtKB/TrEMBL
      Q3TQG5
      Related
      ENSMUSP00000145803.1, OTTMUSP00000074547, ENSMUST00000206325.1, OTTMUST00000142955
      Conserved Domains (3) summary
      cd04979
      Location:21118
      Ig_Semaphorin_C; Immunoglobulin (Ig)-like domain of semaphorin
      smart00410
      Location:26115
      IG_like; Immunoglobulin like
      cl11960
      Location:180259
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      126408448..126415143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507282.3XP_006507345.1  B-lymphocyte antigen CD19 isoform X1

      UniProtKB/TrEMBL
      A0A0X1KG58
      Related
      ENSMUSP00000032968.6, OTTMUSP00000074546, ENSMUST00000032968.6, OTTMUST00000142954
      Conserved Domains (2) summary
      smart00410
      Location:183263
      IG_like; Immunoglobulin like
      cd04979
      Location:21118
      Ig_Semaphorin_C; Immunoglobulin (Ig)-like domain of semaphorin
    2. XM_006507283.2XP_006507346.1  B-lymphocyte antigen CD19 isoform X2

      See identical proteins and their annotated locations for XP_006507346.1

      UniProtKB/Swiss-Prot
      P25918
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