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    Card9 caspase recruitment domain family, member 9 [ Mus musculus (house mouse) ]

    Gene ID: 332579, updated on 13-Dec-2017
    Official Symbol
    Card9provided by MGI
    Official Full Name
    caspase recruitment domain family, member 9provided by MGI
    Primary source
    MGI:MGI:2685628
    See related
    Ensembl:ENSMUSG00000026928 Vega:OTTMUSG00000012770
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm782
    Expression
    Broad expression in large intestine adult (RPKM 6.7), lung adult (RPKM 4.8) and 27 other tissues See more
    Orthologs
    Location:
    2; 2 A3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (26352280..26361530, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (26207832..26215067, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 187 Neighboring gene predicted gene, 35807 Neighboring gene G-protein signalling modulator 1 (AGS3-like, C. elegans) Neighboring gene DNL-type zinc finger Neighboring gene small nuclear RNA activating complex, polypeptide 4 Neighboring gene serologically defined colon cancer antigen 3

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    CARD domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    defense response to Gram-positive bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to virus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of JNK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of JNK cascade ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT positive regulation of NF-kappaB transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of interleukin-6 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of stress-activated MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of stress-activated MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of tumor necrosis factor production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of interleukin-2 biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of interleukin-6 biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of tumor necrosis factor biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to drug IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to exogenous dsRNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to muramyl dipeptide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to peptidoglycan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    caspase recruitment domain-containing protein 9

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037747.1NP_001032836.1  caspase recruitment domain-containing protein 9

      See identical proteins and their annotated locations for NP_001032836.1

      Status: PROVISIONAL

      Source sequence(s)
      AL732541
      Consensus CDS
      CCDS38084.1
      UniProtKB/Swiss-Prot
      A2AIV8
      Related
      ENSMUSP00000097876.3, ENSMUST00000100303.9
      Conserved Domains (2) summary
      cd08809
      Location:1095
      CARD_CARD9; Caspase activation and recruitment domain of CARD9-like proteins
      pfam04156
      Location:78213
      IncA; IncA protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      26352280..26361530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498135.3XP_006498198.1  caspase recruitment domain-containing protein 9 isoform X1

      Conserved Domains (2) summary
      cd08809
      Location:1095
      CARD_CARD9; Caspase activation and recruitment domain of CARD9-like proteins
      pfam06248
      Location:80284
      Zw10; Centromere/kinetochore Zw10
    2. XM_017319060.1XP_017174549.1  caspase recruitment domain-containing protein 9 isoform X2

    3. XM_017319061.1XP_017174550.1  caspase recruitment domain-containing protein 9 isoform X3

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