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    KCS18 3-ketoacyl-CoA synthase 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829603, updated on 14-Dec-2016
    Gene symbol
    KCS18
    Gene description
    3-ketoacyl-CoA synthase 18
    Primary source
    Araport:AT4G34520
    Locus tag
    AT4G34520
    Gene type
    protein coding
    RNA name
    3-ketoacyl-CoA synthase 18
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-ketoacyl-CoA synthase 18; FAE1; FATTY ACID ELONGATION1; T4L20.100; T4L20_100
    Summary
    Encodes KCS18, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
    See KCS18 in Map Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (16494205..16495842)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene 3-ketoacyl-CoA synthase 17 Neighboring gene NmrA-like negative transcriptional regulator family protein Neighboring gene cryptochrome-interacting basic-helix-loop-helix 1 Neighboring gene F-box protein Neighboring gene Ribosomal protein S25 family protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NM_119617.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    3-oxo-arachidoyl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    3-oxo-cerotoyl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    3-oxo-lignoceronyl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    fatty acid elongase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transferase activity, transferring acyl groups ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    fatty acid elongation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    very long-chain fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular region ISM
    Inferred from Sequence Model
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    organelle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    3-ketoacyl-CoA synthase 18
    NP_195178.1
    • 3-ketoacyl-CoA synthase 18 (KCS18); FUNCTIONS IN: fatty acid elongase activity, acyltransferase activity; INVOLVED IN: fatty acid elongation, very long-chain fatty acid metabolic process; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: shoot apex, stem, fruit, carpel; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 9 (TAIR:AT2G16280.1); Has 5011 Blast hits to 4998 proteins in 1240 species: Archae - 0; Bacteria - 1718; Metazoa - 0; Fungi - 14; Plants - 3124; Viruses - 0; Other Eukaryotes - 155 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16494205..16495842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119617.2NP_195178.1  3-ketoacyl-CoA synthase 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195178.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38860
      UniProtKB/TrEMBL
      A0A178UUK5
      Conserved Domains (3) summary
      PLN02932
      Location:10491
      PLN02932; 3-ketoacyl-CoA synthase
      pfam08392
      Location:69368
      FAE1_CUT1_RppA; FAE1/Type III polyketide synthase-like protein
      cl21486
      Location:385465
      Ketoacyl-synt_C; Beta-ketoacyl synthase, C-terminal domain
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