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    Kiss1r KISS1 receptor [ Mus musculus (house mouse) ]

    Gene ID: 114229, updated on 10-Sep-2016
    Official Symbol
    Kiss1rprovided by MGI
    Official Full Name
    KISS1 receptorprovided by MGI
    Primary source
    MGI:MGI:2148793
    See related
    Ensembl:ENSMUSG00000035773
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpr54; KiSS-1
    Orthologs
    Location:
    10; 10 C1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (79916960..79924088)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79379716..79385018)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene complement factor D (adipsin) Neighboring gene mediator complex subunit 16 Neighboring gene R3H domain containing 4 Neighboring gene predicted gene, 40715 Neighboring gene AT rich interactive domain 3A (BRIGHT-like)

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled peptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    G-protein coupled peptide receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neuropeptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    activation of MAPKK activity ISO
    Inferred from Sequence Orthology
    more info
     
    arachidonic acid secretion ISO
    Inferred from Sequence Orthology
    more info
     
    calcium-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell migration IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    negative regulation of cell proliferation IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phospholipase C-activating G-protein coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of hormone secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    kiSS-1 receptor
    Names
    G-protein coupled receptor 54
    G-protein coupled receptor OT7T175
    kiSS-1R
    kisspeptins receptor
    mOT7T175
    metastin receptor
    orphan G protein-coupled receptor 54

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053244.5NP_444474.1  kiSS-1 receptor

      See identical proteins and their annotated locations for NP_444474.1

      Status: VALIDATED

      Source sequence(s)
      AC151846, AK039628, AK139303
      Consensus CDS
      CCDS23998.1
      UniProtKB/Swiss-Prot
      Q91V45
      UniProtKB/TrEMBL
      B2CP06
      Related
      ENSMUSP00000040516, ENSMUST00000045529
      Conserved Domains (2) summary
      pfam00001
      Location:59323
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:51168
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      79916960..79924088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513076.3XP_006513139.1  

      See identical proteins and their annotated locations for XP_006513139.1

      UniProtKB/Swiss-Prot
      Q91V45
      UniProtKB/TrEMBL
      B2CP06
      Conserved Domains (2) summary
      pfam00001
      Location:59323
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:51168
      7tm_4; Olfactory receptor
    2. XM_006513077.3XP_006513140.1  

      See identical proteins and their annotated locations for XP_006513140.1

      UniProtKB/Swiss-Prot
      Q91V45
      UniProtKB/TrEMBL
      B2CP06
      Conserved Domains (2) summary
      pfam00001
      Location:59323
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:51168
      7tm_4; Olfactory receptor
    3. XM_006513078.3XP_006513141.1  

      See identical proteins and their annotated locations for XP_006513141.1

      UniProtKB/TrEMBL
      C5H7S2
      Conserved Domains (2) summary
      pfam00001
      Location:59168
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:53157
      7tm_4; Olfactory receptor
    4. XM_006513079.3XP_006513142.1  

      See identical proteins and their annotated locations for XP_006513142.1

      UniProtKB/TrEMBL
      C5H7S2
      Conserved Domains (2) summary
      pfam00001
      Location:59168
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:53157
      7tm_4; Olfactory receptor
    5. XM_006513080.3XP_006513143.1  

      Conserved Domains (1) summary
      pfam00001
      Location:59167
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RNA

    1. XR_001779418.1 RNA Sequence

    2. XR_380346.3 RNA Sequence

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