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    HSP101 heat shock protein 101 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843771, updated on 10-May-2017
    Gene symbol
    HSP101
    Gene description
    heat shock protein 101
    Primary source
    Araport:AT1G74310
    Locus tag
    AT1G74310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATHSP101; F1O17.2; F1O17_2; heat shock protein 101; HEAT SHOCK PROTEIN ATHSP101; HOT1
    Summary
    Encodes ClpB1, which belongs to the Casein lytic proteinase/heat shock protein 100 (Clp/Hsp100) family. Involved in refolding of proteins which form aggregates under heat stress. Also known as AtHsp101. AtHsp101 is a cytosolic heat shock protein required for acclimation to high temperature.
    See HSP101 in Map Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (27936508..27940369, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene Protein kinase superfamily protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    NM_001334640.1
    NM_106091.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    ATPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    protein unfolding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to heat IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to heat IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    response to heat IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to high light intensity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISM
    Inferred from Sequence Model
    more info
     
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    heat shock protein 101
    NP_565083.1
    • heat shock protein 101 (HSP101); FUNCTIONS IN: protein binding, ATPase activity, ATP binding; INVOLVED IN: response to high light intensity, response to hydrogen peroxide, response to heat, protein unfolding; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Clp ATPase, C-terminal (InterPro:IPR019489), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-2 (InterPro:IPR013093), ATPase, AAA-type, core (InterPro:IPR003959), Chaperonin clpA/B (InterPro:IPR001270), Chaperonin ClpA/B, conserved site (InterPro:IPR018368), Clp, N-terminal (InterPro:IPR004176); BEST Arabidopsis thaliana protein match is: casein lytic proteinase B2 (TAIR:AT4G14670.1); Has 27671 Blast hits to 24472 proteins in 3146 species: Archae - 360; Bacteria - 17866; Metazoa - 1124; Fungi - 430; Plants - 707; Viruses - 13; Other Eukaryotes - 7171 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27936508..27940369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106091.4NP_565083.1  heat shock protein 101 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565083.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42730
      Conserved Domains (6) summary
      cd00009
      Location:182337
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      TIGR03346
      Location:6856
      chaperone_ClpB; ATP-dependent chaperone ClpB
      pfam02861
      Location:1771
      Clp_N; Clp amino terminal domain, pathogenicity island component
      pfam07724
      Location:600761
      AAA_2; AAA domain (Cdc48 subfamily)
      pfam08287
      Location:412489
      DASH_Spc19; Spc19
      pfam10431
      Location:768848
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
    2. NM_001334640.1NP_001320516.1  heat shock protein 101 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7U9, A0A1P8AN20
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