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    PRKCZ protein kinase C zeta [ Bos taurus (cattle) ]

    Gene ID: 286877, updated on 11-Nov-2017
    Official Symbol
    PRKCZprovided by VGNC
    Official Full Name
    protein kinase C zetaprovided by VGNC
    Primary source
    VGNC:VGNC:33336
    See related
    BGD:BT29685; Ensembl:ENSBTAG00000014119
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    Location:
    chromosome: 16
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    105 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 16 AC_000173.1 (51847750..51947503, complement)

    Chromosome 16 - AC_000173.1Genomic Context describing neighboring genes Neighboring gene SKI proto-oncogene Neighboring gene uncharacterized LOC104974459 Neighboring gene Fanconi anemia core complex associated protein 20 Neighboring gene uncharacterized LOC101902612 Neighboring gene gamma-aminobutyric acid type A receptor delta subunit

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

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    Markers

    Homology

    Preferred Names
    protein kinase C zeta type
    NP_001071301.1
    XP_005217075.3
    XP_005217076.1
    XP_005217078.1
    XP_010811612.1
    XP_015330608.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077833.2NP_001071301.1  protein kinase C zeta type

      See identical proteins and their annotated locations for NP_001071301.1

      Status: PROVISIONAL

      Source sequence(s)
      BC126688
      UniProtKB/TrEMBL
      A0JNH7
      Related
      ENSBTAP00000018768.5, ENSBTAT00000018768.5
      Conserved Domains (3) summary
      cd06404
      Location:18100
      PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
      cd00029
      Location:133182
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05617
      Location:238594
      STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Genomic

    1. AC_000173.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

      Range
      51847750..51947503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217021.3XP_005217078.1  protein kinase C zeta type isoform X3

      See identical proteins and their annotated locations for XP_005217078.1

      Conserved Domains (2) summary
      smart00220
      Location:69335
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:53409
      PKc_like; Protein Kinases, catalytic domain
    2. XM_015475122.1XP_015330608.1  protein kinase C zeta type isoform X2

      Conserved Domains (4) summary
      smart00220
      Location:263529
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00029
      Location:142191
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05617
      Location:247603
      STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
      cl02720
      Location:33109
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
    3. XM_005217019.2XP_005217076.1  protein kinase C zeta type isoform X3

      See identical proteins and their annotated locations for XP_005217076.1

      Conserved Domains (2) summary
      smart00220
      Location:69335
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:53409
      PKc_like; Protein Kinases, catalytic domain
    4. XM_005217018.3XP_005217075.3  protein kinase C zeta type isoform X1

      Conserved Domains (3) summary
      smart00220
      Location:289555
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00029
      Location:168217
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05617
      Location:273629
      STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    5. XM_010813310.1XP_010811612.1  protein kinase C zeta type isoform X3

      See identical proteins and their annotated locations for XP_010811612.1

      Conserved Domains (2) summary
      smart00220
      Location:69335
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:53409
      PKc_like; Protein Kinases, catalytic domain

    Alternate Btau_5.0.1

    Genomic

    1. NC_007314.5 Alternate Btau_5.0.1

      Range
      52023819..52123274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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