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    Clec4a2 C-type lectin domain family 4, member a2 [ Mus musculus (house mouse) ]

    Gene ID: 26888, updated on 16-Jul-2017
    Official Symbol
    Clec4a2provided by MGI
    Official Full Name
    C-type lectin domain family 4, member a2provided by MGI
    Primary source
    MGI:MGI:1349412
    See related
    Ensembl:ENSMUSG00000030148 Vega:OTTMUSG00000034576
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DCIR; Dcir1; Clec4a; Clecsf6
    Location:
    6 F2; 6 58.18 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (123122690..123143999)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (123072708..123094017)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 4, member a4 Neighboring gene C-type lectin domain family 4, member b1 Neighboring gene C-type lectin domain family 4, member b2 Neighboring gene peptidylprolyl isomerase A pseudogene 6_1344.1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carbohydrate binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    C-type lectin domain family 4 member A
    Names
    C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6
    C-type lectin superfamily member 6
    dendritic cell immunoreceptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170332.1NP_001163803.1  C-type lectin domain family 4 member A isoform b

      See identical proteins and their annotated locations for NP_001163803.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AC164111, AK049002, BC096565
      Consensus CDS
      CCDS20510.1
      UniProtKB/Swiss-Prot
      Q9QZ15
      Related
      ENSMUSP00000124615.1, OTTMUSP00000047748, ENSMUST00000161365.7, OTTMUST00000087720
      Conserved Domains (1) summary
      cd03590
      Location:107233
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
    2. NM_001170333.1NP_001163804.1  C-type lectin domain family 4 member A isoform a

      See identical proteins and their annotated locations for NP_001163804.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
      Source sequence(s)
      AA387662, AC164111, AK049002
      Consensus CDS
      CCDS51894.1
      UniProtKB/Swiss-Prot
      Q9QZ15
      UniProtKB/TrEMBL
      Q923C7
      Related
      ENSMUSP00000032248.7, OTTMUSP00000047747, ENSMUST00000032248.7, OTTMUST00000087719
      Conserved Domains (1) summary
      cd03590
      Location:131257
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
    3. NM_011999.4NP_036129.1  C-type lectin domain family 4 member A isoform b

      See identical proteins and their annotated locations for NP_036129.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AA387662, AC164111, AK049002
      Consensus CDS
      CCDS20510.1
      UniProtKB/Swiss-Prot
      Q9QZ15
      Related
      ENSMUSP00000045781.6, OTTMUSP00000047746, ENSMUST00000041779.12, OTTMUST00000087718
      Conserved Domains (1) summary
      cd03590
      Location:107233
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      123122690..123143999
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241364.2XP_011239666.1  C-type lectin domain family 4 member A isoform X2

      Conserved Domains (1) summary
      cl02432
      Location:131177
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    2. XM_006506155.1XP_006506218.1  C-type lectin domain family 4 member A isoform X1

      See identical proteins and their annotated locations for XP_006506218.1

      UniProtKB/TrEMBL
      C6EQI8
      Conserved Domains (1) summary
      cd03590
      Location:67193
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
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