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    Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 [ Mus musculus (house mouse) ]

    Gene ID: 16513, updated on 14-Mar-2017
    Official Symbol
    Kcnj10provided by MGI
    Official Full Name
    potassium inwardly-rectifying channel, subfamily J, member 10provided by MGI
    Primary source
    MGI:MGI:1194504
    See related
    Ensembl:ENSMUSG00000044708 Vega:OTTMUSG00000050148
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BIR10; BIRK-1; Kir1.2; Kir4.1
    Orthologs
    Location:
    1 H3; 1 79.69 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (172341210..172374085)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (174271341..174304216)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene immunoglobulin superfamily, member 8 Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 9 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class M Neighboring gene SLAM family member 9 Neighboring gene ribosomal protein SA pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-activated inward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    inward rectifier potassium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inward rectifier potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    potassium channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    voltage-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    L-glutamate import ISO
    Inferred from Sequence Orthology
    more info
     
    adult walking behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    central nervous system myelination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glutamate reuptake IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    membrane hyperpolarization ISO
    Inferred from Sequence Orthology
    more info
     
    oligodendrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    potassium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    potassium ion import IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    potassium ion import ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    potassium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    potassium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein homotetramerization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of long-term neuronal synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of resting membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of sensory perception of pain ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    visual perception IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    astrocyte projection ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    integral component of plasma membrane IC
    Inferred by Curator
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    microvillus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    ATP-sensitive inward rectifier potassium channel 10
    Names
    inward rectifier K(+) channel Kir4.1
    potassium channel, inwardly rectifying subfamily J member 10

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039484.1NP_001034573.1  ATP-sensitive inward rectifier potassium channel 10

      See identical proteins and their annotated locations for NP_001034573.1

      Status: VALIDATED

      Source sequence(s)
      AC074311, AK044640, AK048864
      Consensus CDS
      CCDS15512.1
      UniProtKB/Swiss-Prot
      Q9JM63
      UniProtKB/TrEMBL
      Q56VN0, Q8C7Z5
      Related
      ENSMUSP00000054356, OTTMUSP00000068763, ENSMUST00000056136, OTTMUST00000127496
      Conserved Domains (1) summary
      pfam01007
      Location:31362
      IRK; Inward rectifier potassium channel

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      172341210..172374085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496677.3XP_006496740.2  ATP-sensitive inward rectifier potassium channel 10 isoform X1

      See identical proteins and their annotated locations for XP_006496740.2

      UniProtKB/Swiss-Prot
      Q9JM63
      UniProtKB/TrEMBL
      Q56VN0
      Conserved Domains (1) summary
      pfam01007
      Location:31362
      IRK; Inward rectifier potassium channel

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_020269.3: Suppressed sequence

      Description
      NM_020269.3: This RefSeq was permanently suppressed because it is a nonsense-mediated decay (NMD) candidate.
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