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    recQ ATP-dependent DNA helicase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948318, updated on 25-May-2017
    Gene symbol
    recQ
    Gene description
    ATP-dependent DNA helicase
    Primary source
    EcoGene:EG10833
    Locus tag
    b3822
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3816; JW5855
    Summary
    SSB binds to RecQ and stimulates DNA unwinding (Shereda, 2007). [More information is available at EcoGene: EG10833]. A component of the RecF recombinational pathway, RecQ is a helicase that functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks. [More information is available at EcoCyc: EG10833].
    Sequence:
    NC_000913.3 (4005864..4007693)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 4HBT thioesterase family protein Neighboring gene outer membrane phospholipase A Neighboring gene threonine efflux pump Neighboring gene homoserine, homoserine lactone and S-methyl-methionine efflux pump

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • RNA degradation, organism-specific biosystem (from KEGG)
      RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
    • RNA degradation, conserved biosystem (from KEGG)
      RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP-dependent 3'-5' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ATP-dependent DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-dependent ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    four-way junction helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    single-stranded DNA-dependent ATP-dependent DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transition metal ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    zinc ion binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA recombination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA recombination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA repair IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cellular response to DNA damage stimulus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    bacterial nucleoid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    replisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    single-stranded DNA-dependent ATP-dependent DNA helicase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    ATP-dependent DNA helicase
    YP_026263.3

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4005864..4007693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026263.3 ATP-dependent DNA helicase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026263.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P15043
      Conserved Domains (6) summary
      smart00341
      Location:529609
      HRDC; Helicase and RNase D C-terminal
      PRK11057
      Location:1607
      PRK11057; ATP-dependent DNA helicase RecQ; Provisional
      cd00079
      Location:212339
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:27190
      DEAD; DEAD/DEAH box helicase
      pfam09382
      Location:406513
      RQC; RQC domain
      pfam16124
      Location:344403
      RecQ_Zn_bind; RecQ zinc-binding
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