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    RBFOX1 RNA binding protein, fox-1 homolog 1 [ Homo sapiens (human) ]

    Gene ID: 54715, updated on 9-Jul-2017
    Official Symbol
    RBFOX1provided by HGNC
    Official Full Name
    RNA binding protein, fox-1 homolog 1provided by HGNC
    Primary source
    HGNC:HGNC:18222
    See related
    Ensembl:ENSG00000078328 MIM:605104; Vega:OTTHUMG00000129551
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    2BP1; FOX1; A2BP1; FOX-1; HRNBP1
    Summary
    The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
    Orthologs
    Location:
    16p13.3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 16 NC_000016.10 (5239749..7713343)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (5289469..7763342)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371065 Neighboring gene uncharacterized LOC105371067 Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 14 Neighboring gene long intergenic non-protein coding RNA 2164 Neighboring gene ribosomal protein S3a pseudogene 48 Neighboring gene small nuclear ribonucleoprotein polypeptide C pseudogene 20 Neighboring gene nucleophosmin 1 pseudogene 3 Neighboring gene long intergenic non-protein coding RNA 1570 Neighboring gene microRNA 8065 Neighboring gene RNA, U7 small nuclear 99 pseudogene Neighboring gene RNA, U6 small nuclear 457, pseudogene Neighboring gene uncharacterized LOC105371068 Neighboring gene RNA, U6 small nuclear 328, pseudogene Neighboring gene ribosomal protein S26 pseudogene 51 Neighboring gene uncharacterized LOC105371069 Neighboring gene uncharacterized LOC105371070

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated (2013-06-20)

    ClinGen Genome Curation Page
    Haploinsufficency

    Little evidence for dosage pathogenicity (Last evaluated (2013-06-20)

    ClinGen Genome Curation PagePubMed

    NHGRI GWAS Catalog

    Description
    A genome-wide association study of sleep habits and insomnia.
    NHGRI GWA Catalog
    A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
    NHGRI GWA Catalog
    Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
    NHGRI GWA Catalog
    Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.
    NHGRI GWA Catalog
    Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.
    NHGRI GWA Catalog
    Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative.
    NHGRI GWA Catalog
    Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
    NHGRI GWA Catalog
    Genome-wide association study and meta-analysis of intraocular pressure.
    NHGRI GWA Catalog
    Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
    NHGRI GWA Catalog
    Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.
    NHGRI GWA Catalog
    Genome-wide association study of chronic periodontitis in a general German population.
    NHGRI GWA Catalog
    Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries.
    NHGRI GWA Catalog
    Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
    NHGRI GWA Catalog
    Genome-wide meta-analysis for severe diabetic retinopathy.
    NHGRI GWA Catalog
    Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 Loci.
    NHGRI GWA Catalog
    Genomewide association study of movement-related adverse antipsychotic effects.
    NHGRI GWA Catalog
    Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
    NHGRI GWA Catalog
    Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathway in Allergic Rhinitis.
    NHGRI GWA Catalog
    Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.
    NHGRI GWA Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    NHGRI GWA Catalog
    • MECP2 and Associated Rett Syndrome, organism-specific biosystem (from WikiPathways)
      MECP2 and Associated Rett Syndrome, organism-specific biosystemMecp2 is in many mammals an important regulator of neuronal function and development. It affects all cell types, especially neurons but also astrocytes, oligodendrocytes, and glial cells. Mecp2 plays...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein C-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    RNA transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    RNA binding protein fox-1 homolog 1
    Names
    ataxin 2-binding protein 1
    fox-1 homolog A
    fox-1-like RNA-binding protein 1
    hexaribonucleotide binding protein 1 isoform alpha
    hexaribonucleotide binding protein 1 isoform beta
    hexaribonucleotide-binding protein 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_011881.1 RefSeqGene

      Range
      5001..1699209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001142333.1NP_001135805.1  RNA binding protein fox-1 homolog 1 isoform 5

      See identical proteins and their annotated locations for NP_001135805.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus and other internal differences compared to isoform 1.
      Source sequence(s)
      AB208826, AC005774, AF448859
      Consensus CDS
      CCDS55984.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      UniProtKB/TrEMBL
      Q59HD3
      Related
      ENSP00000447753.1, OTTHUMP00000243974, ENST00000553186.5, OTTHUMT00000409493
      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100252
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:226315
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    2. NM_001142334.1NP_001135806.1  RNA binding protein fox-1 homolog 1 isoform 4

      See identical proteins and their annotated locations for NP_001135806.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and lacks an in-frame section of the 3' coding region, compared to variant 1. This results in a shorter isoform (4) with an alternate N-terminus compared to isoform 1. Variants 4 and 6 both encode isoform 4.
      Source sequence(s)
      AC005774, AF107203, AK001027
      Consensus CDS
      CCDS55983.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      Related
      ENSP00000447717.1, OTTHUMP00000243980, ENST00000547338.5, OTTHUMT00000409499
      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253342
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    3. NM_001308117.1NP_001295046.1  RNA binding protein fox-1 homolog 1 isoform 6

      See identical proteins and their annotated locations for NP_001295046.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the UTRs and has multiple differences in the coding region which results in the use of an alternate start codon and a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (6) has a longer N-terminus and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC005774, AC027683, AK293951
      Consensus CDS
      CCDS76818.1
      UniProtKB/TrEMBL
      B7Z1U7
      Related
      ENSP00000391269.4, OTTHUMP00000243976, ENST00000422070.8, OTTHUMT00000409495
      Conserved Domains (4) summary
      PHA03193
      Location:88155
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:143243
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:160235
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:296385
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    4. NM_018723.3NP_061193.2  RNA binding protein fox-1 homolog 1 isoform 4

      See identical proteins and their annotated locations for NP_061193.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame section of the 3' coding region, compared to variant 1. This results in a shorter isoform (4) with an alternate N-terminus compared to isoform 1. Variants 4 and 6 both encode isoform 4.
      Source sequence(s)
      AB208826, AC005774, AF107203
      Consensus CDS
      CCDS55983.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      UniProtKB/TrEMBL
      Q59HD3
      Related
      ENSP00000450031.1, OTTHUMP00000243973, ENST00000550418.5, OTTHUMT00000409492
      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253342
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    5. NM_145891.2NP_665898.1  RNA binding protein fox-1 homolog 1 isoform 1

      See identical proteins and their annotated locations for NP_665898.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1), also known as gamma, encodes isoform (1).
      Source sequence(s)
      AC005774, AC007222, AF229057
      Consensus CDS
      CCDS10531.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      Related
      ENSP00000309117.5, OTTHUMP00000159949, ENST00000311745.9, OTTHUMT00000251742
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273363
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    6. NM_145892.2NP_665899.1  RNA binding protein fox-1 homolog 1 isoform 2

      See identical proteins and their annotated locations for NP_665899.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2), also known as alpha, lacks an in-frame segment of the 3' coding region, compared to variant 1. This results in a shorter isoform (2) that lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AC005774, AC007222, AF094849
      Consensus CDS
      CCDS45405.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      Related
      ENSP00000402745.2, OTTHUMP00000243981, ENST00000436368.6, OTTHUMT00000409500
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273363
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    7. NM_145893.2NP_665900.1  RNA binding protein fox-1 homolog 1 isoform 3

      See identical proteins and their annotated locations for NP_665900.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3), also known as beta, has an alternate exon in the 3' coding region, compared to variant 1. This results in a shorter isoform (3) with an alternate C-terminus, compared to isoform 1.
      Source sequence(s)
      AC005774, AC007222, AF109106
      Consensus CDS
      CCDS10532.1
      UniProtKB/Swiss-Prot
      Q9NWB1
      Related
      ENSP00000347855.4, OTTHUMP00000159950, ENST00000355637.8, OTTHUMT00000251743
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273360
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p7 Primary Assembly

      Range
      5239749..7713343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017023318.1XP_016878807.1  RNA binding protein fox-1 homolog 1 isoform X1

    2. XM_017023319.1XP_016878808.1  RNA binding protein fox-1 homolog 1 isoform X2

    3. XM_017023335.1XP_016878824.1  RNA binding protein fox-1 homolog 1 isoform X24

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253339
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    4. XM_017023341.1XP_016878830.1  RNA binding protein fox-1 homolog 1 isoform X30

    5. XM_017023328.1XP_016878817.1  RNA binding protein fox-1 homolog 1 isoform X14

      Conserved Domains (4) summary
      PHA03193
      Location:88155
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:143243
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:160235
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:296382
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    6. XM_017023324.1XP_016878813.1  RNA binding protein fox-1 homolog 1 isoform X9

      Conserved Domains (4) summary
      PHA03193
      Location:88155
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:143243
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:160235
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:296385
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    7. XM_017023329.1XP_016878818.1  RNA binding protein fox-1 homolog 1 isoform X16

      Conserved Domains (4) summary
      PHA03193
      Location:88155
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:143295
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:160235
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:269358
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    8. XM_017023326.1XP_016878815.1  RNA binding protein fox-1 homolog 1 isoform X12

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253339
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    9. XM_005255390.3XP_005255447.1  RNA binding protein fox-1 homolog 1 isoform X11

      See identical proteins and their annotated locations for XP_005255447.1

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253340
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    10. XM_017023320.1XP_016878809.1  RNA binding protein fox-1 homolog 1 isoform X3

      Conserved Domains (4) summary
      PHA03193
      Location:88155
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:143243
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:160235
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:296383
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    11. XM_017023322.1XP_016878811.1  RNA binding protein fox-1 homolog 1 isoform X5

      Related
      ENSP00000438768.2, OTTHUMP00000243978, ENST00000535565.6, OTTHUMT00000409497
      Conserved Domains (4) summary
      PHA03193
      Location:81148
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:136236
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:153228
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:289375
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    12. XM_017023321.1XP_016878810.1  RNA binding protein fox-1 homolog 1 isoform X4

      Conserved Domains (4) summary
      PHA03193
      Location:81148
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:136236
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:153228
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:289376
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    13. XM_017023330.1XP_016878819.1  RNA binding protein fox-1 homolog 1 isoform X17

      Related
      ENSP00000448496.1, OTTHUMP00000243977, ENST00000552089.5, OTTHUMT00000409496
    14. XM_017023336.1XP_016878825.1  RNA binding protein fox-1 homolog 1 isoform X24

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253339
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    15. XM_017023333.1XP_016878822.1  RNA binding protein fox-1 homolog 1 isoform X20

      UniProtKB/Swiss-Prot
      Q9NWB1
      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253342
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    16. XM_017023342.1XP_016878831.1  RNA binding protein fox-1 homolog 1 isoform X30

    17. XM_017023338.1XP_016878827.1  RNA binding protein fox-1 homolog 1 isoform X26

      UniProtKB/Swiss-Prot
      Q9NWB1
      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100252
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:226315
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    18. XM_017023340.1XP_016878829.1  RNA binding protein fox-1 homolog 1 isoform X29

    19. XM_005255391.3XP_005255448.1  RNA binding protein fox-1 homolog 1 isoform X11

      See identical proteins and their annotated locations for XP_005255448.1

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253340
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    20. XM_017023325.1XP_016878814.1  RNA binding protein fox-1 homolog 1 isoform X11

      Conserved Domains (4) summary
      PHA03193
      Location:45112
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:100200
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:117192
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:253340
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    21. XM_017023332.1XP_016878821.1  RNA binding protein fox-1 homolog 1 isoform X19

    22. XM_017023327.1XP_016878816.1  RNA binding protein fox-1 homolog 1 isoform X13

    23. XM_017023337.1XP_016878826.1  RNA binding protein fox-1 homolog 1 isoform X25

    24. XM_017023334.1XP_016878823.1  RNA binding protein fox-1 homolog 1 isoform X21

    25. XM_017023323.1XP_016878812.1  RNA binding protein fox-1 homolog 1 isoform X7

    26. XM_005255386.3XP_005255443.1  RNA binding protein fox-1 homolog 1 isoform X6

      Conserved Domains (4) summary
      PHA03193
      Location:70137
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:125225
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:142217
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:278365
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    27. XM_011522547.2XP_011520849.1  RNA binding protein fox-1 homolog 1 isoform X22

      See identical proteins and their annotated locations for XP_011520849.1

      UniProtKB/TrEMBL
      X5D7T5
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273359
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    28. XM_011522546.2XP_011520848.1  RNA binding protein fox-1 homolog 1 isoform X15

      See identical proteins and their annotated locations for XP_011520848.1

      UniProtKB/TrEMBL
      X5DNY3
      Related
      ENSP00000344196.4, ENST00000340209.8
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273362
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    29. XM_011522548.2XP_011520850.1  RNA binding protein fox-1 homolog 1 isoform X28

      See identical proteins and their annotated locations for XP_011520850.1

      UniProtKB/TrEMBL
      X5DP44
      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120272
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:246332
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    30. XM_005255394.4XP_005255451.1  RNA binding protein fox-1 homolog 1 isoform X23

      See identical proteins and their annotated locations for XP_005255451.1

      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120272
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:246336
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    31. XM_005255387.3XP_005255444.1  RNA binding protein fox-1 homolog 1 isoform X8

      See identical proteins and their annotated locations for XP_005255444.1

      Conserved Domains (4) summary
      PHA03193
      Location:65132
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:120220
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:137212
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273360
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    32. XM_017023331.1XP_016878820.1  RNA binding protein fox-1 homolog 1 isoform X18

      Conserved Domains (4) summary
      PHA03193
      Location:2592
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:80180
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:97172
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:233320
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    33. XM_005255388.4XP_005255445.1  RNA binding protein fox-1 homolog 1 isoform X10

      See identical proteins and their annotated locations for XP_005255445.1

      Conserved Domains (4) summary
      PHA03193
      Location:47114
      PHA03193; tegument protein VP11/12; Provisional
      COG0724
      Location:102202
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:119194
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:255342
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    34. XM_017023343.1XP_016878832.1  RNA binding protein fox-1 homolog 1 isoform X31

    35. XM_017023339.1XP_016878828.1  RNA binding protein fox-1 homolog 1 isoform X27

    Alternate CHM1_1.1

    Genomic

    1. NC_018927.2 Alternate CHM1_1.1

      Range
      6071131..7764167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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