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    RPH1 Rph1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856916, updated on 5-Mar-2017
    Gene symbol
    RPH1
    Gene description
    Rph1p
    Primary source
    SGD:S000000971
    Locus tag
    YER169W
    Gene type
    protein coding
    RNA name
    Rph1p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    KDM4
    See RPH1 in Map Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (523369..525759)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Bck2p Neighboring gene tRNA adenylyltransferase Neighboring gene adenylate kinase ADK2 Neighboring gene TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Component Evidence Code Pubs
    nucleus IC
    Inferred by Curator
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Rph1p
    NP_011096.1
    • JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      523369..525759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179059.1NP_011096.1  TPA: Rph1p [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_011096.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P39956
      Conserved Domains (6) summary
      smart00545
      Location:1354
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:222338
      JmjC; JmjC domain, hydroxylase
      COG5048
      Location:507759
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:711732
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:723749
      zf-H2C2_2; Zinc-finger double domain
      pfam13894
      Location:709732
      zf-C2H2_4; C2H2-type zinc finger
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