Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Il27 interleukin 27 [ Mus musculus (house mouse) ]

    Gene ID: 246779, updated on 25-May-2017
    Official Symbol
    Il27provided by MGI
    Official Full Name
    interleukin 27provided by MGI
    Primary source
    MGI:MGI:2384409
    See related
    Ensembl:ENSMUSG00000044701 Vega:OTTMUSG00000029446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p28; Il30; IL-27; IL-27p28
    Orthologs
    Location:
    7; 7 F3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (126589009..126595021, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133732809..133738424, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit C Neighboring gene ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) Neighboring gene microRNA 7059 Neighboring gene apolipoprotein B receptor Neighboring gene predicted gene, 39086 Neighboring gene predicted gene, 39087 Neighboring gene nuclear protein transcription regulator 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    interleukin-27 receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of defense response to virus by host IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of defense response to virus by host IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of interferon-gamma biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of interferon-gamma biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of T cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of T-helper 1 cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of T-helper 1 cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    interleukin-27 subunit alpha
    Names
    IL-27 p28 subunit
    IL-27 subunit alpha
    IL-27-A
    IL27-A
    interleukin 30

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145636.1NP_663611.1  interleukin-27 subunit alpha precursor

      See identical proteins and their annotated locations for NP_663611.1

      Status: PROVISIONAL

      Source sequence(s)
      AY099297
      Consensus CDS
      CCDS21835.1
      UniProtKB/Swiss-Prot
      Q8K3I6
      Related
      ENSMUSP00000054637.5, OTTMUSP00000037686, ENSMUST00000058429.5, OTTMUST00000072967

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      126589009..126595021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507857.1XP_006507920.1  interleukin-27 subunit alpha isoform X1

    Support Center