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    Ptprs protein tyrosine phosphatase, receptor type, S [ Mus musculus (house mouse) ]

    Gene ID: 19280, updated on 22-Apr-2017
    Official Symbol
    Ptprsprovided by MGI
    Official Full Name
    protein tyrosine phosphatase, receptor type, Sprovided by MGI
    Primary source
    MGI:MGI:97815
    See related
    Ensembl:ENSMUSG00000013236 Vega:OTTMUSG00000014929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PTP; Ptpt9; PTP-NU3; PTPNU-3; R-PTP-S; AL022616; PTPsigma; RPTPsigma
    Orthologs
    Location:
    17 D; 17 29.32 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (56412426..56476480, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (56551849..56615903, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-like, containing PHD and RING finger domains, 1 Neighboring gene lysine (K)-specific demethylase 4B Neighboring gene predicted gene, 32715 Neighboring gene microRNA 6977 Neighboring gene predicted gene, 33032 Neighboring gene predicted gene, 32822 Neighboring gene predicted gene 9258 Neighboring gene predicted gene, 33089

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC90571

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chondroitin sulfate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heparin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoprotein phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein tyrosine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cerebellum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    corpus callosum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    establishment of endothelial intestinal barrier IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hippocampus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of axon regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of collateral sprouting IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of dendritic spine development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of interferon-alpha production ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of interferon-beta production ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of toll-like receptor 9 signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-tyrosine dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptidyl-tyrosine dephosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    spinal cord development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of postsynaptic density membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    receptor-type tyrosine-protein phosphatase S
    Names
    R-PTP-sigma
    Receptor-type tyrosine-protein phosphatase sigma
    tissue-specific protein tyrosine phosphatase
    NP_001239382.1
    NP_001239384.1
    NP_001239385.1
    NP_035348.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252453.1NP_001239382.1  receptor-type tyrosine-protein phosphatase S isoform 2 precursor

      See identical proteins and their annotated locations for NP_001239382.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks four consecutive exons in the coding region, but maintains the reading frame, compared to variant 1. Variants 2 and 4 encode the same isoform (2), which is shorter than isoform 1.
      Source sequence(s)
      BC052462, CT009637
      Consensus CDS
      CCDS57103.1
      UniProtKB/Swiss-Prot
      B0V2N1
      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:9451200
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:9711200
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    2. NM_001252455.1NP_001239384.1  receptor-type tyrosine-protein phosphatase S isoform 3 precursor

      See identical proteins and their annotated locations for NP_001239384.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks 5 exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AI845699, BC083188, CT009637
      UniProtKB/Swiss-Prot
      B0V2N1
      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:9411196
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:9671196
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    3. NM_001252456.1NP_001239385.1  receptor-type tyrosine-protein phosphatase S isoform 2 precursor

      See identical proteins and their annotated locations for NP_001239385.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and lacks four consecutive exons in the coding region, but maintains the reading frame, compared to variant 1. Variants 2 and 4 encode the same isoform (2), which is shorter than isoform 1.
      Source sequence(s)
      CT009637
      Consensus CDS
      CCDS57103.1
      UniProtKB/Swiss-Prot
      B0V2N1
      Related
      ENSMUSP00000084038.3, OTTMUSP00000015869, ENSMUST00000086828.9, OTTMUST00000035455
      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:9451200
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:9711200
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    4. NM_011218.2NP_035348.2  receptor-type tyrosine-protein phosphatase S isoform 1 precursor

      See identical proteins and their annotated locations for NP_035348.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AI845699, AK163915, BC083188, CJ177868, D28530
      Consensus CDS
      CCDS37664.1
      UniProtKB/Swiss-Prot
      B0V2N1
      UniProtKB/TrEMBL
      Q3TQ52
      Related
      ENSMUSP00000064048.5, OTTMUSP00000015868, ENSMUST00000067538.5, OTTMUST00000035454
      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13511606
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13771606
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      56412426..56476480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523881.1XP_006523944.1  receptor-type tyrosine-protein phosphatase S isoform X8

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:9491204
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:9751204
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    2. XM_006523874.1XP_006523937.1  receptor-type tyrosine-protein phosphatase S isoform X1

      See identical proteins and their annotated locations for XP_006523937.1

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13641619
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13901619
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    3. XM_017317350.1XP_017172839.1  receptor-type tyrosine-protein phosphatase S isoform X10

    4. XM_006523880.2XP_006523943.1  receptor-type tyrosine-protein phosphatase S isoform X6

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13071562
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13331562
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    5. XM_006523876.2XP_006523939.1  receptor-type tyrosine-protein phosphatase S isoform X2

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13601615
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13861615
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    6. XM_006523879.2XP_006523942.1  receptor-type tyrosine-protein phosphatase S isoform X5

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13111566
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13371566
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    7. XM_006523878.2XP_006523941.1  receptor-type tyrosine-protein phosphatase S isoform X4

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13201575
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13461575
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    8. XM_006523877.2XP_006523940.1  receptor-type tyrosine-protein phosphatase S isoform X3

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13551610
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13811610
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    9. XM_006523875.3XP_006523938.1  receptor-type tyrosine-protein phosphatase S isoform X1

      See identical proteins and their annotated locations for XP_006523938.1

      Conserved Domains (8) summary
      cd05738
      Location:152226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:250318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:13641619
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141225
      IG_like; Immunoglobulin like
      cd00047
      Location:13901619
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:323412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32120
      Ig; Immunoglobulin domain
    10. XM_017317349.1XP_017172838.1  receptor-type tyrosine-protein phosphatase S isoform X7

    11. XM_006523882.2XP_006523945.1  receptor-type tyrosine-protein phosphatase S isoform X9

      Conserved Domains (3) summary
      smart00194
      Location:7541009
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:7801009
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319407
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    12. XM_006523884.2XP_006523947.1  receptor-type tyrosine-protein phosphatase S isoform X11

      See identical proteins and their annotated locations for XP_006523947.1

      Conserved Domains (3) summary
      smart00194
      Location:665920
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:691920
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:230318
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    13. XM_006523883.2XP_006523946.1  receptor-type tyrosine-protein phosphatase S isoform X11

      See identical proteins and their annotated locations for XP_006523946.1

      Conserved Domains (3) summary
      smart00194
      Location:665920
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:691920
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:230318
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    14. XM_006523886.2XP_006523949.1  receptor-type tyrosine-protein phosphatase S isoform X12

      Conserved Domains (3) summary
      smart00194
      Location:644899
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:670899
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:209297
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RNA

    1. XR_385302.1 RNA Sequence

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